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Quality of Life clinical trials

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NCT ID: NCT05819840 Recruiting - Quality of Life Clinical Trials

Vascular Structure, Vascular Function and Vascular Aging in Adults Diagnosed With Persistent COVID

ICOPER
Start date: March 9, 2023
Phase:
Study type: Observational

The ICOPER study aims to analyze the structure, vascular function, vascular aging and determining factors in 300 adults diagnosed with Persistent Covid in the field of Primary Health Care.

NCT ID: NCT05817513 Recruiting - Quality of Life Clinical Trials

EFFECT OF MYOFASCIAL RELEASE ON SCOLIOTIC CURVATURE AND PREMENSTRUAL SYMPTOMS IN FEMALES WITH DYSMENORRHEA

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

PURPOSE: The purpose of this study is to determine the effect of myofascial release on spinal curvature, premenstrual symptoms, and quality of life in scoliotic females with dysmenorrhea

NCT ID: NCT05817305 Recruiting - Clinical trials for Cardiovascular Diseases

Integrating Exercise Into Lifestyle of Cardiac Outpatients

ITER
Start date: January 1, 1997
Phase:
Study type: Observational [Patient Registry]

The purpose of the study is to investigate the long-term effects of a personalized physical activity program on exercise capacity and quality of life in patients with stable cardiovascular disease. The analysis also intends to evaluate the prognostic value of cardiovascular function estimated through a walking test (1km Treadmill Walking Test, 1k-TWT) in relation to survival, hospitalization, and medical costs. The program considers clinical, socio-economic, and behavioural aspects, psychological support, and risk factor control. Patients receive indications for carrying out a home training program based on the performance of moderate-intensity aerobic activity at least 3-4 days a week for at least 30-60 minutes a day. All patients are also encouraged to improve their daily habits by preferring a more active lifestyle both at home and at work.

NCT ID: NCT05812183 Recruiting - Quality of Life Clinical Trials

Gastric Sleeve-Induced Weight Loss on Shortness of Breath in Obesity

Start date: July 9, 2023
Phase: N/A
Study type: Interventional

Most research to date on bariatric surgery outcomes has been about metabolic syndrome, a disorder very effectively treated by bariatric surgery. However, obesity is also associated with many other problems that have received much less attention. Amongst the most troubling of these for patients is dyspnea. Dyspnea results in substantial patient distress that can greatly reduce health-related quality of life. Little is known about the relationship between dyspnea, weight loss, and bariatric surgery. Dyspnea is a complex symptom that may lead to adaptive responses, such as the need to rest as a consequence of even minimal activity or seeking medical attention. The main outcome of the study will be measured using a new state-of-the-science validated HRQOL measure, the Patient Reported Outcome Measuring Information System for Heart Failure (PROMIS+HF 27).

NCT ID: NCT05810259 Recruiting - Depression Clinical Trials

Assessing the Effectiveness of Digital Wellness Modules on Perceived Quality of Life

Start date: May 22, 2024
Phase: N/A
Study type: Interventional

The study will examine the role of digital wellness modules (brief mindfulness and light to moderate physical exercise) delivered through a smartphone wellness application and their short-term effects on health behavior motivation and change, and longer-term quality of life and non-pathological affective states.

NCT ID: NCT05810155 Recruiting - Quality of Life Clinical Trials

Delayed Surgery in Inflammatory Bowel Disease

Start date: January 8, 2023
Phase:
Study type: Observational [Patient Registry]

The timing of elective surgery in inflammatory bowel disease (IBD) may be crucial according to progression of the disease. In most cases, medical treatment has failed when surgery is discussed. If treatment with surgery then is delayed, complications may arise, such as fistula, severe inflammation with risk of perforation or stenosis, nutrition problems i.e. This may affect quality of life, and also make the surgery more complicated, with higher risk of per- and postoperative complications. The COVID-19 pandemic led to a shift in resources where elective surgery has been postponed. The waiting time for elective surgery for IBD-patients at Sahlgrenska University Hospital/Östra is still affected which might have impact on patient health outcomes as well as health economics, due to the risk of complications and need of emergency and planned care while waiting for surgery. The primary object is to evaluate how long an IBD patient can wait for surgery before affecting health economy and quality of life. In the operation program Orbit, we identify all patients with ulcerative colitits (UC) and Crohn´s disease (CD) that stands in line for elective surgery (not including dysplasia/cancer). The date when operation was decided is registered including time of delay. Patient characteristics are registered in CRF, including diagnosis, age and reason for scheduled surgery. Number of hospital visits (planned/emergency visits) are registered during time of waiting for surgery. Days of sick leave is registered from the Swedish Social Insurance Agency. Questionnaires are sent to the patients for quality of life and bowel function (EQ5D and Short Health Scale). The primary endpoint in the first manuscript is how health economics is affected by the delay of elective care in IBD-patients, due to complications and extensive need of hospital visits while waiting for surgery, costs of medical material (stoma bandage i.e), costs of medical treatment and sick leave rates, including quality of life. Patients who have been operated for IBD will form the control group and comparison will be made in terms of complications, hospital visits, costs of medical material and medical treatment and sick leave rates, as well as quality of life.

NCT ID: NCT05803811 Recruiting - Quality of Life Clinical Trials

Effect of Colon Delivered Vitamin B2 on Gut Microbiota and Related Health Biomarkers in Healthy Older Adults

Start date: December 12, 2022
Phase: N/A
Study type: Interventional

The goal of this intervention study (clinical trial) is to investigate the effect of colon-delivered Riboflavin (vitamin B2) on the faecal microbial composition and diversity in older healthy subjects (50 -70 years of age)

NCT ID: NCT05803499 Recruiting - Quality of Life Clinical Trials

Rest to Overcome Loss and Reduce Risk

RESTore Plus
Start date: March 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to develop and optimize a targeted behavioral intervention for sleep disturbance among individuals who have recently lost a spouse/long-term cohabitating partner. In the first phase of this study, patient focus groups were conducted to gather information about the unique sleep challenges experienced by spousally bereaved individuals and the kinds of support they would like to receive from a program based on Cognitive Behavior Therapy for Insomnia (CBT-I). In the second phase of the study, a two-arm randomized controlled trial will be conducted to compare changes in sleep and inflammation among participants in the targeted CBT-I intervention to those in an information-only control. Participants will be asked to attend two in-person visits (at baseline and, approx. 8 weeks later, at post-treatment) to provide a blood sample and have vital signs and basic anthropometric measurements (height, weight, waist circumference) taken. After their baseline visit, participants will be randomized into either the targeted CBT-I intervention or the information-only control. The targeted CBT-I intervention will entail 6 online sessions (approx. 50 mins. each) delivered via videoconference by a trained facilitator, once per week over the course of approx. 6 weeks. The information-only control will entail 1 online session (approx. 50 mins.) delivered via videoconference by a trained facilitator. Sleep data (collected via both actigraphy watches and patient self-report sleep diaries) and data on mood, grief, and sleep habits will be collected from participants at three timepoints (baseline, post-treatment, and then again at a 6-month follow-up).

NCT ID: NCT05802459 Recruiting - Quality of Life Clinical Trials

Evaluation of the Functional Status of Jejunoplasty and Coloplasty and Its Impact on Quality of Life (CEREC)

CEREC
Start date: December 15, 2022
Phase:
Study type: Observational [Patient Registry]

The goal of this prospective population-based cohort study is to assess: - The evolution of the functional status of patients undergoing complex esophageal reconstruction - Its impact on quality of life, depending on the type of conduit performed. Participants - Will be asked to complete different quality of life questionnaires during every follow-up visit - Will undergo additional tests to assess functionality

NCT ID: NCT05794269 Recruiting - Quality of Life Clinical Trials

Turkish Version of the QoR-15 for Emergency Laparotomy

QoR-15T-EL
Start date: February 1, 2023
Phase:
Study type: Observational

Patient perceived quality of recovery is an important outcome after surgery and should be measured in clinical trials. The QoR-15 was designed to measure quality of recovery postoperatively. It provided an efficient evaluation of the postoperative quality of recovery. The primary objectives of this study is validate the Turkish version of QoR-15 questionnaire for emergency laparotomy. The investigators will test its validity, reliability, responsiveness, and clinical acceptability and feasibility, with patients emergency laparotomy, in the University of Health Sciences, Gülhane Education and Training Hospital Ankara, Türkiye.