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Early Detection of Pulmonary- and Pulmonary Vascular Disease in Sjögren Syndrome

Pulmonary Hypertension Clinical Trial

Official title:
Early Detection of Pulmonary- and Pulmonary Vascular Disease in Patients Suffering From Sjögren Syndrome

Clinical Trial Summary

According to the literature available pulmonary hypertension is present in 12 to 23% of patients suffering from Sjögren Syndrome. However epidemiological data are based on non-invasive measurements using echocardiography. Furthermore, no data are available regarding exercise hemodynamics in those patients.

This study investigates pulmonary hemodynamics at rest and during exercise in patients suffering from primary and secondary Sjögren Syndrome. Patients under suspicion for pulmonary hypertension (PH) will be offered further investigations including right heart catheterization.

Clinical Trial Description

Patients with primary and secondary Sjögren Syndrome will be investigated using echocardiography, exercise echocardiography, pulmonary function testing, laboratory testing, electrocardiogram and 6 minute walking test. Those patients under clinical suspicion for pulmonary hypertension will be offered further investigations including right heart catheterization to rule out or verify the diagnosis of manifest pulmonary hypertension. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02752269
Study type Observational
Source Medical University of Graz
Contact
Status Completed
Phase
Start date October 2014
Completion date June 30, 2019
View Details
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