Fixed Dose Heparin Study

Status Completed

Clinical Trial Summary

FIDO was a multicentred randomized, open-label trial that compared fixed-dose UFH with fixed-dose LMWH for initial treatment of VTE. Patients were followed for 3 months during which they received warfarin (target INR 2.0-3.0).

Clinical Trial Description

The general objective was to simplify and reduce the cost of treatment of acute venous thromboembolism (VTE).Specific objectives were to compare the efficacy, safety and cost effectiveness of unfractionated heparin (UFH) and low molecular weight heparin (LMWH) when each is administered subcutaneously (sc), twice daily, in weight -adjusted, fixed doses; and to determine if the anticoagulant response (anti-Factor Xa heparin levels, APTT results) influence efficacy and safety of UFH and LMWH, independently of dose. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00182403
Study type	Interventional
Source	McMaster University
Contact
Status	Completed
Phase	Phase 3
Start date	September 1998
Completion date	May 2004

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