PTSD Clinical Trial
Official title:
Modification of Cognitive Processing Therapy (CPT-C) for Posttraumatic Stress Disorder (PTSD) and Alcohol Dependence (AD)
Objective: To develop a detailed treatment manual that modifies the existing CPT-C treatment
protocol to allow for concurrent treatment of PTSD and AD, and to obtain some pilot data
regarding its efficacy.
Hypothesis: We predict that CPT-C will significantly reduce the number of drinking days
(measured by the Timeline Follow Back Method [TLFB]) and reduce the symptoms of PTSD
(measured by the [CAPS and PCL] scores).
Design: This is a non-randomized, prospective study in which all participants will receive
the modified CPT-C for 12 weeks by trained CPT-C clinicians, with each session lasting
approximately 1-1.5 hours). Modifications to CPT-C include psychoeducation about alcohol use
as an avoidance of PTSD symptoms integrated throughout treatment, integration of coping
skills training for AD, weekly breathalyzer tests to measure blood alcohol level, and use
and collection of daily dairies of alcohol use.
n/a
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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