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Psoriasis clinical trials

View clinical trials related to Psoriasis.

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NCT ID: NCT06176768 Recruiting - Plaque Psoriasis Clinical Trials

A Study of LY3972406 in Adult Participants With Moderate-to-Severe Plaque Psoriasis

Start date: December 6, 2023
Phase: Phase 2
Study type: Interventional

The main purpose of this study is to determine the efficacy and safety of LY3972406 in adult participants with moderate-to-severe plaque psoriasis.

NCT ID: NCT06172426 Completed - Psoriasis Clinical Trials

Incidence of Psoriatic Arthritis Among Psoriasis Patients Newly Initiated With Secukinumab in a US Claims Database and a UK Registry

Start date: November 17, 2022
Phase:
Study type: Observational

This was a retrospective cohort study to assess the incidence rate of psoriatic arthritis (PsA) among psoriasis (PsO) patients newly initiated on secukinumab or any biologics/apremilast (small molecule). The analysis was performed in two databases, IBM® MarketScan® database: Commercial Claims and Encounters (CCAE) and Medicare Supplemental Beneficiaries (MDCR) from 01 January 2010 to 30 June 2021 and BADBIR from 01 January 2016 to 01 September 2021.

NCT ID: NCT06170840 Recruiting - Psoriasis Clinical Trials

A Study of QY101 Ointment in Subjects With Plaque Psoriasis

Start date: May 17, 2023
Phase: Phase 2
Study type: Interventional

The goal of this clinical trial is to evaluate the effectiveness of QY101 ointment in adult patients with plaque psoriasis (2-20% BSA).

NCT ID: NCT06165887 Not yet recruiting - Clinical trials for Moderate-to-severe Psoriasis

The Relationship Between Moderate-to-severe Psoriasis and Sleep Disturbance

Start date: February 2024
Phase:
Study type: Observational

Psoriasis is a common chronic and systemic immune-mediated disease, induced by a combination of genetic and environmental effects. The increasingly worrying question is the negative impact on patients' sleep, which has become an important comorbidity of psoriasis. To investigate the causal relationship between psoriasis and sleep status, a prospective cohort study will be conducted by separating moderate-to-severe psoriasis patients and healthy individuals into distinct cohorts in order to observe their sleep status.

NCT ID: NCT06164860 Active, not recruiting - Clinical trials for Obesity and Psoriasis

The Effect of Ketogenic Diet Versus Mediterranean Diet in Patients With Obesity and Psoriatic Arthritis

Start date: May 20, 2020
Phase: Phase 4
Study type: Interventional

The aim of our study is to compare the effectiveness of Mediterranean diet (MD) with the isocaloric Ketogenic diet (KD) on clinical and biochemical markers of inflammation in patients with obesity, psoriasis (PSO) and psoriatic arthritis (PsA).

NCT ID: NCT06156280 Recruiting - Psoriasis Clinical Trials

A Clinical Study of TQH2929 in Healthy Adult Subjects

Start date: November 21, 2023
Phase: Phase 1
Study type: Interventional

This project is divided into a single dose escalation and a multiple dose escalation phase Ia clinical study. This is a single-center, randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, and pharmacokinetic characteristics of TQH2929 injection in healthy adults.

NCT ID: NCT06150794 Not yet recruiting - Nail Psoriasis Clinical Trials

Methotrexate Alone vs Combination With Excimer Light in Nail Psoriasis

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to compare the efficacy of excimer laser in combination with intralesional MTX injection to intralesional MTX injection alone in treating nail psoriasis

NCT ID: NCT06143878 Recruiting - Plaque Psoriasis Clinical Trials

A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis

Start date: January 17, 2024
Phase: Phase 3
Study type: Interventional

The purpose of the study is to see how effective JNJ-77242113 is in participants with moderate to severe plaque psoriasis compared to placebo and deucravacitinib.

NCT ID: NCT06143371 Recruiting - Healthy Clinical Trials

A Study to Investigate the Safety and Tolerability of CAN10 Antibody in Healthy Subjects and in Subjects With Plaque Psoriasis.

Start date: August 21, 2023
Phase: Phase 1
Study type: Interventional

This is a first-in-human, randomized, double- blind, placebo-controlled, dose escalation study to investigate how different doses of CAN10 are tolerated, taken up by the body and how long CAN10 stays in the body. In the first part of the study, the single ascending dose (SAD) cohorts, CAN10 will be given as a single intravenous dose to healthy subjects. In the second part of the study, the multiple ascending dose (MAD) cohorts, CAN10 will be given as repeated subcutaneous doses to participants with mild to moderate plaque psoriasis.

NCT ID: NCT06142357 Recruiting - Clinical trials for Moderate-to-severe Plaque Psoriasis

Secukinumab Drug Survival, Effectiveness and Tolerability in Pediatric Patients With Psoriasis

SPARROW
Start date: December 29, 2023
Phase:
Study type: Observational

Multicenter, non-interventional, cohort study in pediatric patients with moderate to severe plaque-type psoriasis. Retrospective data collection is planned at patients' inclusion.