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Psoriasis clinical trials

View clinical trials related to Psoriasis.

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NCT ID: NCT06126718 Not yet recruiting - Psoriasis Clinical Trials

Phase I Randomized, Open-label, Parallel-controlled, Pharmacokinetic and Safety Study of BR201 Injection Versus Cosentyx in Healthy Male Subjects

Start date: November 2023
Phase: Phase 1
Study type: Interventional

This is a randomized, open-label, controlled Phase I study of BR201 administered by subcutaneous injection. This study will characterize the pharmacokinetic, safety and immunogenicity of BR201 versus Cosentyx(Secukinumab ) in healthy male subjects after a single dose.

NCT ID: NCT06125808 Active, not recruiting - Psoriasis Clinical Trials

Efficacy and Safety Study of HRO350 in Patients With Mild-to-moderate Psoriasis (the 'HeROPA' Study).

HeROPA
Start date: May 25, 2023
Phase: Phase 2
Study type: Interventional

HRO350 contains an oil-based extract from herring roe (Clupea harengus) in soft capsules and contains phospholipids (complex lipids) which are naturally rich in marine polyunsaturated fatty acids. All the lipids in HRO350 are natural components of the human diet. It is not fully known how HRO350 exerts its effects, however there are indications that it might have a modulatory effect on the inflammatory processes involved in causing psoriasis. The study is a randomised, double-blind, placebo controlled, dose finding, multi-centre, phase 2B study. Approximately 519 patients will be participating in the UK, Norway, Germany, Finland and Poland. Patients will receive either 1050mg or 2100mg HRO0350 daily, or placebo for up to 52 weeks and will be followed up for a further 8 weeks.

NCT ID: NCT06122649 Recruiting - Plaque Psoriasis Clinical Trials

A Study to Investigate Efficacy and Safety of Apremilast 30 mg Twice Daily (BID) in Chinese Participants With Moderate to Severe Plaque-type Psoriasis (PsO)

ESSENCE
Start date: November 27, 2023
Phase: Phase 3
Study type: Interventional

The study aims to evaluate the clinical efficacy of oral apremilast 30 mg BID compared with placebo in Chinese participants with moderate to severe PsO

NCT ID: NCT06110676 Recruiting - Psoriasis Clinical Trials

A Study to Evaluate the Efficacy and Safety of LZM012

Psoriasis
Start date: August 21, 2023
Phase: Phase 3
Study type: Interventional

This study is a muti-center, randomized, double blind, positive control phase III clinical study to evaluate the efficacy and safety of LZM012 in moderate to severe chronic plaque psoriasis patients

NCT ID: NCT06109818 Recruiting - Clinical trials for Moderate to Severe Plaque Psoriasis

Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of ICP-488 in Patients With Moderate to Severe Plaque Psoriasis

Start date: January 4, 2024
Phase: Phase 2
Study type: Interventional

This is a multicenter, randomized, double-blind, placebo-controlled Phase II clinical study to evaluate ICP-488.Efficacy, safety, PK, and PD characteristics in Chinese adults with moderate to severe plaque psoriasis.

NCT ID: NCT06108544 Recruiting - Plaque Psoriasis Clinical Trials

A Study About How Well TAK-279 Works and Its Safety in Participants With Moderate-to-severe Plaque Psoriasis During 60 Weeks of Treatment With a Withdrawal and Retreatment Period

Start date: November 6, 2023
Phase: Phase 3
Study type: Interventional

The main aim of this study is to show how well TAK-279 reduces the skin plaques compared to placebo, in participants with moderate-to-severe plaque psoriasis. Participants will be assigned to one of the 3 study treatments (TAK-279, apremilast (an approved treatment), or a placebo). Participants will be in the study for up to 69 weeks.

NCT ID: NCT06106230 Completed - Plaque Psoriasis Clinical Trials

Bee Venom Phonophoresis on Mild to Moderate Localized Plaque Psoriasis on Knee Joint

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

Chronic plaque psoriasis, or psoriasis vulgaris, is a chronic inflammatory skin disease characterized by well demarcated, erythematous, scaly plaques on the extensor surfaces of the body and scalp. The lesions may occasionally itch or sting, and may bleed when injured. Dystrophic nail changes or nail pitting are found in more than one third of people with chronic plaque psoriasis, and psoriatic arthropathy occurs in 1% to more than 10%. The condition waxes and wanes, with wide variations in course and severity among individuals.

NCT ID: NCT06104644 Recruiting - Plaque Psoriasis Clinical Trials

A Study to Evaluate Deucravacitinib in Participants With Moderate-to-Severe Plaque Psoriasis in Germany (DELPHIN)

DELPHIN
Start date: April 13, 2023
Phase:
Study type: Observational

The purpose of this observational study is to describe the effectiveness of deucravacitinib treatment and quality of life in adults with moderate-to-severe plaque psoriasis in routine clinical practice in Germany over a 5-year period

NCT ID: NCT06103695 Completed - Psoriasis Clinical Trials

Vtama in Psoriasis Patients Being Treated With Biologics.

Start date: February 27, 2023
Phase: Phase 4
Study type: Interventional

Open label study to assess 12 weeks of add-on VTAMA® (tapinarof) Cream, 1% QD in patients with ≥3% BSA who have received biologic therapy for at least 24 weeks.

NCT ID: NCT06102356 Recruiting - Psoriasis Clinical Trials

Impact of Clinical and Psychological Factors on Treatment Satisfaction in Psoriatic Patients in Biological Therapy

PsoSAT
Start date: September 13, 2023
Phase:
Study type: Observational

This study aims to identify, through the use of questionnaires, demographic, clinical and psychological factors that could better correlate with the satisfaction of psoriatic patients in systemic therapy with biological drugs for more than a year belonging to the Dermatology Clinics of the A. Gemelli-IRCCS University Hospital