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Prostatic Hyperplasia clinical trials

View clinical trials related to Prostatic Hyperplasia.

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NCT ID: NCT04245566 Not yet recruiting - Clinical trials for Benign Prostatic Hyperplasia

Prostatic Artery Embolization vs. Pharmacotherapy for LUTS/BPH

EMPATHY
Start date: September 2021
Phase: Phase 3
Study type: Interventional

This study compares safety and efficacy of prostatic artery embolization and pharmacotherapy in the treatment of lower urinary tract symptoms associated wit benign prostatic hyperplasia.

NCT ID: NCT04243824 Withdrawn - Clinical trials for Benign Prostatic Hyperplasia

Ga-68 MAA Distribution in PAE Patients

Start date: May 2021
Phase: Early Phase 1
Study type: Interventional

Purpose: The purpose of this study is to evaluate Ga-68 MAA distribution on PET/MRI after injection into the prostatic arteries in patients without prostate cancer who are being treated with prostate artery embolization for benign prostatic hyperplasia. Participants: Study subjects will be 5 men scheduled to undergo the PAE procedure at UNC Hospital for benign prostatic hyperplasia. Procedures (methods): Study subjects will undergo PAE using the standard technique. Prior to embolization of the prostatic artery with the bland embolic agent, Ga-68 MAA will be injected. Standard departmental radiation protection procedures will be followed. After the PAE procedure is complete, the patient will be transported to the UNC Biomedical Research Imaging Center to undergo PET/MRI.

NCT ID: NCT04236687 Not yet recruiting - Clinical trials for Benign Prostatic Hyperplasia

Prostate Artery Embolization Compared to Holmium Laser Enucleation of the Prostate for Benign Prostatic Hyperplasia

Start date: February 1, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate improvement of symptoms from benign prostatic hyperplasia (BPH) as assessed by the International Prostate Symptom Score (IPSS) for prostate artery embolization (PAE) with microspheres (Embozene™, 400µm) compared to conventional Holmium laser enucleation of the prostate (HoLEP).

NCT ID: NCT04212403 Completed - Bladder Cancer Clinical Trials

Antibiotic Prophylaxis in Transurethral Prostate Resection (TURP) and Transurethral Bladder Tumour Resection (TURB)

Prophylaxis001
Start date: September 17, 2018
Phase: N/A
Study type: Interventional

To investigate the use of antibiotic prophylaxis in patients undergoing TURP and TURB. The investigators set up a prospective, randomized controlled trial in which (after exclusion of risk factors) patients will be randomized in receiving levofloxacin (Tavanic) orally or no antibiotics. The exclusion criteria for TURP are a pre-operative transurethral catheter or > 100 urinary white blood cells in the pre-operative urine sample. The exclusion criteria for TURB are a pre-op catheter or clinical signs of infection.

NCT ID: NCT04198103 Active, not recruiting - Clinical trials for Lower Urinary Tract Symptoms

Transperineal Laser Ablation for Percutaneous Treatment of Benign Prostatic Hyperplasia

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

This study investigated the effectiveness and safety of SoracteLite ™- Trans-Perineal Laser ablation (TPLA) in the treatment of patients with symptomatic Benign Prostatic Hyperplasia (BPH) at 6 and 12 months follow-up

NCT ID: NCT04185441 Recruiting - Clinical trials for Erectile Dysfunction

Efficacy and Safety of Tanzânia Association in the Treatment of Erectile Dysfunction Associated With Benign Prostatic Hyperplasia

Start date: March 14, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of Tanzânia association in adults with erectile dysfunction associated with Benign Prostatic Hyperplasia.

NCT ID: NCT04178811 Completed - Clinical trials for Benign Prostatic Hyperplasia (BPH)

HoLEP in Management of BPH Patients With Predominant Voiding vs Storage LUTS: A Comparative Retrospective Study

Start date: August 1, 2021
Phase:
Study type: Observational

Comparison in outcomes of a minimally invasive surgical modality (Holmium Laser Enucleation of Prostate) in management of voiding versus storage lower urinary tract symptoms associated with Benign Prostatic Hyperplasia

NCT ID: NCT04146103 Completed - Clinical trials for Benign Prostatic Hyperplasia

A Pumpkin Seed, Isoflavonoid and Cranberry Mix in LUTS/BPH

Start date: April 1, 2018
Phase: N/A
Study type: Interventional

The aim is to assess the efficacy of a mix of Pumpkin Seed Extract, Soy Germ Isoflavonoids and Cranberry (Novex®) in the management of mild to moderate LUTS in BPH patients. The patients will be evaluated based on the severity of LUTS, urological quality of life, and erectile function.

NCT ID: NCT04131907 Active, not recruiting - Clinical trials for Benign Prostatic Hyperplasia

A Clinical Study to Evaluate the Safety and Efficacy of the Optilume™ BPH Catheter System in Men With Symptomatic BPH

PINNACLE
Start date: February 5, 2020
Phase: N/A
Study type: Interventional

PINNACLE is a prospective, multi-center, randomized control clinical trial to establish the safety and efficacy of the Optilume™ BPH Catheter System in the treatment of benign prostatic hyperplasia (BPH)

NCT ID: NCT04108871 Recruiting - Prostate Cancer Clinical Trials

Whether Transperineal Prostate Biopsy Under Local-anaesthesia Using a Transperineal-access System is Non-inferior to Standard Transrectal Biopsy to Detect Prostate Cancer in Biopsy-naïve Men

Start date: October 3, 2018
Phase: N/A
Study type: Interventional

Tranperineal prostate biopsy(TPB) and Transrectal prostate biopsy(TRUSB) are now both routine diagnosis methods of prostate cancer in Queen Mary Hospital. The TRUSB has been the most common way to sample prostate tissue for decades. The TPB has been employed as one of our routine diagnosis methods in early 2018. The aim of this study is to evaluate whether Tranperineal prostate biopsy using a noval transperineal access system under local anaesthesia is non-inferior to standard 12-cores Transrectal prostate biopsy in detecting prostate cancer (PCa), in patients with clinical suspicion of PCa with no prior prostate biopsy.