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Prostatic Hyperplasia clinical trials

View clinical trials related to Prostatic Hyperplasia.

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NCT ID: NCT04331301 Completed - Clinical trials for Prostatic Hyperplasia

Bipolar Needlescopic Enucleation Versus Vapoenucleation of BPH

Start date: January 10, 2017
Phase: N/A
Study type: Interventional

Transurethral resection of the prostate (TURP) is the current standard procedure for men with prostate volume 30-80 gm. In case with large prostate adenoma (>80 g), the resection time required by TURP is associated with increased risk of TUR syndrome, blood loss and other complications. Many types of minimally invasive surgery exist along with new equipment and techniques. Many types of laser devices such as greenlight laser, thulium laser and holmium laser, are used to enucleate the prostate. Increasing evidence has proven their safety and efficacy However, the use of laser devices is difficult and associated with steep learning curve and high medical expenses. PKEP is a safe and effective procedure for the treatment of bladder obstruction secondary to BPH. This procedure not only improves maximum flow rate at 3 and 12 months after surgery, but it also improves all other recorded parameters (IPSS, QOL, IEFF-5, PVR, PSA). A button electrode can be effectively used to enucleate the prostate because of its powerful vaporisation and strong coagulation (B-TUEP technique) ,such as that with a holmium laser, thulium laser and greenlight laser. However its associated with short term complication as early irritative symptoms, Bulai reported that 16.7% of the patients suffering from early irritative symptoms while Geavlete reported that 11.4% of patient suffering from early irritative symptoms.

NCT ID: NCT04309695 Recruiting - Clinical trials for Benign Prostatic Hyperplasia

The Zenflow Spring System Safety and Performance Study (ZEST CAN)

Start date: February 9, 2021
Phase: N/A
Study type: Interventional

The objectives of the trial are to demonstrate the safety and performance of the Zenflow Spring System in relieving the symptoms of obstructive Benign Prostatic Hyperplasia (BPH).

NCT ID: NCT04308070 Completed - Clinical trials for Benign Prostatic Hyperplasia

Acute Hemostasis Following the Use of the AQUABEAM® System for the Treatment of Benign Prostatic Hyperplasia III

AHAIII
Start date: July 18, 2017
Phase: N/A
Study type: Interventional

A dual-arm prospective, interventional clinical trial to evaluate the safety and performance of obtaining hemostasis with catheters along with the use or absence of a hemostatic agent following treatment with the AQUABEAM System.

NCT ID: NCT04288427 Recruiting - Clinical trials for Benign Prostatic Hyperplasia

5-Alpha Reductase 2 as a Marker of Resistance to 5ARI Therapy

Start date: September 25, 2020
Phase: N/A
Study type: Interventional

The study is being conducted to learn why some patients with Benign Prostatic Hyperplasia (BPH) do not respond to a commonly used treatment drug, Finasteride. The hope is to find ways to predict which patients will not respond to Finasteride so that, in the future, these patients can be identified prior to offering this treatment and they can be offered alternative treatment strategies in its place. The aim is to see if noninvasive techniques such as MRI can detect inflammation of the prostate to assist with early detection of those who will and who will not respond to Finasteride.

NCT ID: NCT04275076 Completed - Clinical trials for Prostate Hyperplasia

HoLEP Vs BPEP for Large Prostatic Adenoma

enucleation
Start date: February 1, 2018
Phase: Phase 3
Study type: Interventional

Benign prostatic hyperplasia (BPH) is one of the most common urinary disorders in elderly males. The symptoms of BPH include impaired physiological and functional well-being, which interferes with daily living. At present, transurethral resection of the prostate (TURP) is the standard surgical treatment. However, the high rate of complications associated with TURP is a major drawback of this procedure. Holmium laser enucleation of the prostate (HoLEP) was proven to be an effective surgical treatment for BPH with no prostate size limitation with adequate hemostasis, bipolar enucleation of the prostate (BPEP) has been introduced as an alternative energy source with a promising outcome with equal safety and efficacy

NCT ID: NCT04272216 Completed - Clinical trials for Benign Prostatic Hyperplasia

An Observational Study of Radial Access Embolization Procedures Using HydroPearl Microspheres

RAVI Registry
Start date: February 6, 2020
Phase:
Study type: Observational [Patient Registry]

This registry study is designed to collect data on the procedural success and complication rates in real-world patients undergoing HydroPearl embolization procedures via radial access.

NCT ID: NCT04271020 Completed - Clinical trials for Benign Prostatic Hyperplasia

Urodynamic Feasibility Study Utilizing the UroLift® System

UDS
Start date: October 25, 2018
Phase: N/A
Study type: Interventional

UDS evaluates the impact of Prostatic Urethral Lift (PUL) as measured by pressure flow, urodynamic testing (UDS) and an optional UroCuff Testing, an alternative urodynamic test. In addition, standard BPH measures such as symptoms, qualify of life, uroflowmetry, and post void residual will be evaluated at screening and at the follow-up visits.

NCT ID: NCT04267445 Not yet recruiting - Clinical trials for Benign Prostatic Hyperplasia

Evaluate the Safety and Effectiveness of Using Echogenic Embolic Agent for Embolization of Prostate Artery for Treatment of Men With BPH (PAE CEUS)

PAE CEUS
Start date: March 2020
Phase:
Study type: Observational [Patient Registry]

A prospective single centre study to evaluate the safety and effectiveness of using contrast enhanced ultrasound and echogenic embolic agent Ekobi Embolization Microspheres in Prostate Artery Embolization for the Treatment of Men with Benign Prostatic Hyperplasia

NCT ID: NCT04266418 Recruiting - Clinical trials for Benign Prostatic Hyperplasia (BPH)

The Evaluation of Banana Flower Stamens Extract on Prevention of Benign Prostatic Hyperplasia in Adults

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

To assess the evaluation of banana flower stamens extract on prevention of benign prostatic hyperplasia in adults

NCT ID: NCT04263987 Completed - Clinical trials for Benign Prostatic Hyperplasia

A Comparison of Traditional and MOSES Laser Enucleation of the Prostate (MOLEP): A Prospective, Randomized, Double-blinded Control Trial A Comparison of Traditional and MOSES Laser Enucleation of the Prostate (MOLEP): A Prospective, Randomized, Double-blinded Control Trial

Start date: January 1, 2020
Phase: Phase 3
Study type: Interventional

Holmium laser enucleation of the prostate (HOLEP) has proven to be efficacious and safe for the treatment of benign prostatic hypertrophy (BPH). New laser technologies such as the Moses Pulse laser system provide for improved energy delivery which may decrease blood loss and operative time. We seek to evaluate Moses technology for enucleation of the prostate in the setting of BPH.