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Clinical Trial Summary

The percentage of malignant prostate tumors detected very early is constantly increasing and the number of well differentiated tumors, with small volume and low risk of progression increases. When a tumor of this type is identified, radical prostatectomy remains the reference treatment, but this treatment is not without side effects. Active surveillance is a strategy which aims at detecting an early development of the cancerous disease in order to propose curative treatment in a timely manner and thus improve specific survival. Patients are therefore re-evaluated each year by rectal examination, PSA (Prostate-Specific Antigen) assay. Active surveillance remains difficult to manage psychologically for both the patient and the practitioner, because of the lack of treatment on the one hand and a rate of non-curable cancers close to 50% when signs of progression trigger a radical treatment.

The aim of the focal treatment HIFU (High Intensity Focused Ultrasound) is to destroy the cancer without causing side effects in contrast to radical treatments. It is in this sense that it is positioned both as an alternative to radical surgery and as an alternative to active surveillance.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03531099
Study type Interventional
Source Hospices Civils de Lyon
Contact Sébastien CROUZET, Pr
Phone 04 72 11 03 25
Email sebastien.crouzet@chu-lyon.fr
Status Not yet recruiting
Phase Phase 3
Start date July 1, 2018
Completion date July 1, 2023

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