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Premature clinical trials

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NCT ID: NCT06285669 Completed - Clinical trials for Respiratory Distress Syndrome

Effects of Kinesiotaping on Respiratory Muscles in Very Preterm Infants

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

This study aimed to evaluate the effects of kinesio taping on blood gas parameters, respiratory rate, heart rate, oxygen saturation, and pressure limits in preterm infants with RDS who are on NIV. It is hypothesized that the application of kinesio taping to the chest area of preterm infants may improve respiratory functions and oxygenation at the alveolar level, leading to decreased work of breathing, reduced respiratory rate, and improved neonatal stability by promoting respiratory mechanics and enhancing chest expansion.

NCT ID: NCT06082674 Completed - Premature Clinical Trials

Novel Low Cost Bubble CPAP as an Alternative Respiratory Support in Low Resource Setting

Start date: April 1, 2022
Phase: Phase 2
Study type: Interventional

This is a single-blind randomized controlled trial done in a Level III neonatal intensive care unit. Preterm newborns with RDS were randomized to receive oxygen therapy through bubble CPAP vs ventilator-derived CPAP. Differences in arterial blood gases, oxygen saturation, number of surfactant and CPAP failure rate between study groups were analyzed.

NCT ID: NCT05948098 Completed - Pain Clinical Trials

Facilitated Tucking Position, Gentle Human Touch Practices and Pain

Start date: July 20, 2023
Phase: N/A
Study type: Interventional

This prospective study is planned as a randomized controlled study to evaluate the effect of facilitated tucking position and gentle human touch practices on the pain experienced by newborns during heel blood collection. This study is planned to be carried out between 15 July and 15 December 2023 in the neonatal intensive care unit of a training and research hospital in the Southeastern Anatolia Region. The sample size was calculated based on the study of premature infants to determine the effect of facilitated tucking position on procedural pain. According to the results of the study, PIPP pain scores were determined as 11.88±3.05 in the intervention group (n=17) and 9.06±2.95 in the control group (n=17). The effect size of the study was determined as d= 0.939 at α=0.05 level and 95% confidence interval. It was decided to conduct the study with a total of 90 premature babies, 30 of whom were in the groups, in case of data loss during the study.

NCT ID: NCT05860166 Completed - Infant Development Clinical Trials

Development of a Scale for Evaluation of Neuromotor Development of Infants

Start date: March 16, 2022
Phase: N/A
Study type: Interventional

Although the scales used so far provide information about the neuromotor progression of a single baby, it is thought that they are not sufficient to distinguish babies from each other, and it is thought that there is no assessment battery that will adapt to the knowledge in their conditions and the functional development of babies. Therefore, the aim of our study is to reveal the applicability and psychometric properties of the Neonatal Infant Motor Assessment Scale (NIMAS) test, which reveals the neurological and motor performance of infants hospitalized in the NICU, both as automatic responses and functional behavior.

NCT ID: NCT05801640 Completed - Feeding Behavior Clinical Trials

Facilitated Tucking Position and Reiki Efficacy in Orogastric Tube Insertion

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to determine the effects of faciliated tucking and reiki given manually during orogastric tube insertion in preterm infants treated in the NICU on stress, pain and physiological parameter (heartbeat, blood pressure, SpO2 and respiratory rate) levels.

NCT ID: NCT05496400 Completed - Premature Clinical Trials

Anemia of Prematurity and Hemodynamics

Start date: July 1, 2021
Phase:
Study type: Observational

The aim of this work to study the hemodynamic changes accompanying anemia of prematurity in neonates with gestational age ≤32 weeks and the effect of its treatment on hemodynamics.

NCT ID: NCT05210959 Completed - Infant Development Clinical Trials

The Turkish Version of the Affordances in the Home Environment for Motor Development-Infant Scale (AHEMD-IS)

AHEMD-IS
Start date: April 1, 2021
Phase:
Study type: Observational [Patient Registry]

The Affordances in the Home Environment for Motor Development-Infant Scale (AHEMD-IS) is an instrument that assesses the quality and quantity of motor development opportunities available in the home for infants aged 3 to 18 months. Since its initial publication, the AHEMD-IS has grown in popularity as a clinical tool and research criterion. Furthermore, the AHEMD-IS supports the claim that environmental factors can have a positive impact on future motor skills and later cognitive behaviors of infants. Also it is stated that environmental factors are associated with infant motor development and motor abilities. As of writing, it has been translated into eight languages from the original English version and has been reported as valid and reliable in countries such as China, Spain, Lebanon, and Persia. The aim of this study was to produce the Turkish version of the AHEMD-IS and to reveal the validity and reliability of this version.

NCT ID: NCT05180058 Completed - Premature Clinical Trials

Development and Efficiency of Atraumatic Orogastric Tube Insertion Protocol With Combination of Wrapping, Fetal Position, Breastmilk, and Sucrose

OGT
Start date: February 15, 2022
Phase: N/A
Study type: Interventional

This study aimed to reduce the pain and increase comfort during the orogastric tube insertion (OGT) procedure, which is routinely applied to feed these babies at 32-34 weeks of age, in preterm newborns with a sucking reflex.In addition, this study also aimed to develop an atraumatic OGT attachment protocol by combining wrapping, fetal position, breast milk and oral sucrose combined therapy. It was planned as a randomized double-blind and controlled experimental study to evaluate the efficacy of using In addition, this study also planned to develop the atraumatic OGT insertion procedure through combined therapy of wrapping, fetal position, breast milk, and oral sucrose. The population of the research consists of preterm babies who are treated in the Neonatal Intensive Care Unit of Selcuk University Hospital. Babies to be sampled are preterm babies who are between 32 and 34 weeks of gestation. Preterm newborns will be randomly divided into five groups; - Group 1: Control - Group 2: Wrapping + breast milk (2 ml) - Group 3: Wrapping + oral sucrose (0.2 ml/kg 20% sucrose) - Group 4: Fetal position + breast milk (2 ml) - Group 5: Fetal position + oral sucrose (0.2 ml/kg 20% sucrose) In the NICU, OGT insertion will be performed by the clinical nurse as part of the treatment for preterm newborns, which the clinic physician deems necessary. The clinical nurse and clinician will be responsible for OGT insertion in preterm newborns. In this study, only wrapping, fetal positioning, oral breast milk and sucrose delivery methods will be applied to preterm newborns by the researcher. In this context, the responsibility of the researcher in the study will be to apply non-pharmacological methods to preterm newborns only before OGT insertion and to evaluate the pain symptoms in preterm newborns during and after OGT insertion. The obtained data will be evaluated in SPSS-21 package program in computer environment. Normality tests, chi-square, t test, Anova, and advanced analysis will be used when necessary in the analysis of the data. The relationship between the mean score of the scale and other variables will be evaluated by correlation regression analysis. Significance will be accepted as p<0.05.

NCT ID: NCT05095285 Completed - Premature Clinical Trials

Pain and Comfort During Endotracheal Suction in Premature Neonates

Start date: July 1, 2019
Phase: N/A
Study type: Interventional

Most of the preterm babies in neonatal units are followed up with invasive mechanical ventilation support. For this reason, endotracheal suction is needed repeatedly in preterm babies in order to open the airway obstruction caused by secretions and to maintain the airway patency. Endotracheal aspiration, which is one of the invasive procedures in which pain is felt most in newborns, is performed by nurses. Endotracheal suction, which causes pain and discomfort in intensive care units, negatively affects the comfort of patients. Studies emphasize that comfort is an indicator of pain and stress, and the comfort scale is also used in pain and distress assessments. Effective pain management and the development of pain-related care standards to reduce pain in preterm newborn infants improve clinical and neurodevelopmental outcomes. For this reason, it is necessary to reduce the pain that has an effect on the development of preterm babies. In pediatric nursing, studies on non-pharmacological methods have increased in recent years in order to increase the comfort of infants and reduce pain and stress, especially during painful and stressful procedures in infants followed in neonatal intensive care units. When the literature is examined, there are few studies measuring the effectiveness of non-pharmacological methods used in reducing pain due to endotracheal suction. There are differences in the effectiveness of the methods applied in the existing studies. Therefore, more observation, research and scientific studies by neonatal nurses are needed to reduce the pain associated with endotracheal suction in preterm newborns. In this study, swaddling and oropharyngeal colostrum, which are two non-pharmacological methods, will be applied during endotracheal suction to preterm newborns receiving invasive mechanical ventilation support. This experimental study was planned to determine the effect of these two non-pharmacological methods on procedural pain and comfort and to contribute to evidence-based nursing practices.

NCT ID: NCT05036603 Completed - Preterm Birth Clinical Trials

Comparison of the Acute Effects of Chest Physiotherapy Methods Applied in Different Positions in Preterm Newborns

therapy
Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Infants in the neonatal intensive care unit (NICU) may be lost due to risks such as being sensitive, frequent exposure to birth complications and being prone to infection. The most common causes of mortality in newborn babies in the world; Complications due to preterm delivery (28%), infections (26%) and perinatal asphyxia (23%) were reported. Respiratory problems are observed in 4-6% of newborns. These problems are also important causes of mortality in the neonatal period. Newborn infants are more likely to have respiratory distress due to difficulties in airway calibration, few collateral airways, flexible chest wall, poor airway stability, and low functional residual capacity.Invasive mechanical ventilation (IMV) is frequently used in the treatment of newborns with respiratory failure. Various ventilation modes and strategies are used to optimize mechanical ventilation and prevent ventilator-induced lung injury. Among the important issues to be considered in newborns connected to mechanical ventilator (MV); Choosing an appropriately sized endotracheal tube to reduce airway resistance and minimize respiratory workload, correct positioning, regular nursing care, chest physiotherapy, sedation-analgesia, and infection prevention are also included.