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Pregnancy clinical trials

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NCT ID: NCT05207644 Completed - Pregnancy Clinical Trials

Letrozole and Misoprostol for Termination of Pregnancy up to 63 Days' Gestation

Start date: December 9, 2021
Phase: Phase 2
Study type: Interventional

Study to determine if a user-friendly medical abortion regimen using letrozole and misoprostol is safe and acceptable.

NCT ID: NCT05094479 Completed - Pregnancy Clinical Trials

E-health App and Lifestyle Changes During Pregnancy

E-HEALTH
Start date: June 21, 2017
Phase: N/A
Study type: Interventional

The purpose of this online follow-up study is to investigate health app use in pregnant women and through a pilot intervention trial investigate whether the addition of evidence-based information on health-promoting lifestyle delivered via the health app has an effect on lifestyle habits (gestational weight, diet quality and physical activity) during pregnancy.

NCT ID: NCT05070468 Completed - Pregnancy Clinical Trials

Effect of Dexamethasone on Labor Induction

Start date: November 22, 2020
Phase: Phase 3
Study type: Interventional

Pregnant women with a gestational age of 38 weeks and older admitted to Labor Of Kamali Hospital, for termination of pregnancy, by accident and based on the coding done by a statistician to identify groups of users of pill A or pill B, 14 pills are used vaginally . The client and the researcher are blinded and the pharmacist delivers the dexamethasone and placebo tablets with codes A and B to the researcher.

NCT ID: NCT05063799 Completed - Pregnancy Clinical Trials

Pulmonary Rehabilitation After Pregnancy in COVID-19 Infection: A Case Report

Start date: October 10, 2021
Phase: N/A
Study type: Interventional

The 33-month pregnant patient was followed in the gynecology service with the complaint of shortness of breath after receiving the covid positive diagnosis and was transferred to the intensive care unit due to acute respiratory failure. She was intubated in the intensive care unit and the baby was taken by cesarean section. Pulmonary rehabilitation steps to be applied to the patient with long-term intensive care hospitalization will be examined.

NCT ID: NCT05047419 Completed - Asthma Clinical Trials

Asthma in Pregnancy

Start date: August 27, 2021
Phase:
Study type: Observational

The long-term goal is to improve the care of patients with asthma. The overarching objective of this pilot grant is to test the feasibility, acceptability and potential clinical utility of deploying a mobile-health intervention to improve asthma surveillance.

NCT ID: NCT05033041 Completed - Pregnancy Clinical Trials

Gastric Volumes by US in Term Parturients Undergoing CS With and Without Metoclopramide

Start date: October 20, 2021
Phase: Phase 4
Study type: Interventional

Our objective is to compare gastric volumes (mL) between women who receive metoclopramide versus placebo prior to scheduled cesarean delivery in appropriately fasted patients. If metoclopramide is found not to reduce gastric volumes this would inform future practice guidelines for obstetric anesthesia, which currently recommends metoclopramide administration prior to cesarean deliveries. We hypothesize that metoclopramide given to women with appropriate fasting prior to cesarean delivery does not result in any clinically significant reduction in gastric volume (mL) and therefore does not provide any additional benefit for aspiration prophylaxis but may expose patients to unnecessary side effects. A secondary objective will be to evaluate if gastric volume is a significant predictor of intraoperative nausea and vomiting.

NCT ID: NCT05022979 Completed - Pregnancy Clinical Trials

Prevalence and Risk Factors for Micronutrient Deficiencies During Pregnancy in Cayenne, French Guiana

CarMa
Start date: May 28, 2018
Phase:
Study type: Observational

Micronutrient deficiencies are frequent in pregnant women in French Guiana, a French territory in South America. Micronutrient deficiencies are more frequent in precarious women. Obesity is a frequent problem but it is also associated with micronutrient deficiency. Micronutrient deficiencies have largely been overlooked in this outermost European region and should be corrected.

NCT ID: NCT05001906 Completed - Pregnancy Clinical Trials

Pregnant Women With Physical Activity

GineVeiw
Start date: December 1, 2020
Phase: N/A
Study type: Interventional

Physical activity, defined as any movement of the body produced by the contraction of skeletal muscles in all phases of life, maintains and improves cardiorespiratory capacity, reduces the risk of obesity and associated comorbidities. The study will analyze the effect of prenatal exercise on circulatory functional and structural parameters and gestational weight gain in pregnant women who exercised regularly, compared to pregnant women who did not exercise regularly.

NCT ID: NCT04941534 Completed - Pregnancy Clinical Trials

This Clinical Study Evaluates the Performance and Safety of Biorithm Research Kit Versus CTG in Prenatal Monitoring of Pregnant Participants.

Start date: June 4, 2021
Phase:
Study type: Observational

This clinical study will evaluate the safety and comparative performance of Biorithm Research Kit vs CTG (gold standard) in prenatal monitoring of pregnant participants.

NCT ID: NCT04913948 Completed - Covid19 Clinical Trials

Assessing the Mother-to-infant Transmission Capabilities of COVID-19 Infection Among Pregnant Women in Ontario, Canada

COPE
Start date: April 30, 2020
Phase:
Study type: Observational

In order to assess the mother-to-infant and potential vertical transmission of SARS-CoV-2 infection in pregnant women, maternal and neonatal biological samples will be prospectively collected from women with confirmed or suspected COVID-19 at participating hospitals across Ontario. Samples will be tested for the SARS-CoV-2 serology and viral load. Outcomes for the study objective will be ascertained through the collection and testing of biological samples from the mother and/or infant. Specifically the investigators will: 1. Assess maternal nasopharyngeal or oropharyngeal swab, vaginal mucosa, ano-rectal swab, amniotic fluid, placenta (including subamniotic swab), breastmilk, cord blood and neonatal nasopharyngeal swab for RNA particles of coronavirus, by ddPCR. 2. Assess maternal serum for anti-coronavirus antibodies, by immunoassay. 3. Examine the impact of coronavirus on the neonate with respect to serology and viral load, in addition to placenta pathology findings and ddPCR. 4. Assess vertical transmission and the effect of coronavirus through placental pathology examination using placental pathology synoptic report.