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Pregnancy clinical trials

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NCT ID: NCT06401629 Not yet recruiting - Pregnancy Clinical Trials

Outcomes After Unified Versus Standard GDM Diagnosis

UPDATE-GDM
Start date: January 1, 2025
Phase: N/A
Study type: Interventional

Gestational diabetes mellitus (GDM) is a condition that can affect pregnant women during pregnancy and may cause complications for the mother and the baby. Therefore, early and accurate detection is necessary to provide the woman and the baby with better health outcomes. Currently, the most commonly used criteria to detect GDM is the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criterion. However, there is a suggestion that it results in over-diagnosis of GDM, and newer methods of diagnosis have been proposed. One such proposal is to have more than a binary outcome of assessment of dysglycemia in pregnancy. The investigator group created this criterion known as the National Priorities Research Program (NPRP) criterion. This clinical trial compares the IADPSG to the NPRP criteria in pregnant women in Qatar to determine if this newer method mitigates overdiagnosis and more accurately identifies women at risk of complications.

NCT ID: NCT06391151 Not yet recruiting - Pregnancy Clinical Trials

Effect of OSA Resulting From Chronic Tonsillitis on Pregnancy Outcomes

Start date: May 15, 2024
Phase:
Study type: Observational

This cohort study aims to investigate the impact of obstructive sleep apnea hypopnea syndrome (OSA) resulting from chronic tonsillitis on pregnancy outcomes. The hypothesis posits that chronic tonsillitis-induced OSA may exacerbate pregnancy complications and increase the risk of adverse pregnancy outcomes.

NCT ID: NCT06391138 Not yet recruiting - Pregnancy Clinical Trials

The Effect of OSA on Pregnancy and Fetal Outcomes

Start date: May 15, 2024
Phase:
Study type: Observational

This cohort study aims to investigate the impact of obstructive sleep apnea hypopnea syndrome (OSA) on pregnancy and fetal outcomes. The hypothesis posits that OSA may aggravate pregnancy complications, elevate the risk of adverse pregnancy outcomes, and potentially impact fetal development.

NCT ID: NCT06336434 Not yet recruiting - Pregnancy Clinical Trials

CREATE - Cabotegravir & Rilpivirine Antiretroviral Therapy in Pregnancy

Start date: September 24, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

This is a Phase I/II, multicenter, open-label, non-randomized study with four groups to characterize the pharmacokinetics and safety of Cabotegravir (CAB) and Rilpivirine (RPV) long-acting injectable (LA) during pregnancy and postpartum among people with HIV-1 viral suppression and their infants.

NCT ID: NCT06312644 Not yet recruiting - Pregnancy Clinical Trials

Study of Ultomiris® (Ravulizumab) Safety in Pregnancy

Start date: March 29, 2024
Phase:
Study type: Observational [Patient Registry]

The primary objective of this study is to describe the frequency and characteristics of pregnancy outcomes and maternal complications among participants exposed to Ultomiris and to describe the frequency and characteristics of selected fetal/neonatal/infant outcomes in utero, at birth, and through 1 year of age after exposure in utero or via breastmilk.

NCT ID: NCT06270056 Not yet recruiting - Pregnancy Clinical Trials

Evaluation of Telemedicine Medical Abortion Service in Ecuador

Start date: February 2024
Phase:
Study type: Observational

This research seeks to demonstrate that a telemedicine model for the provision of legal abortion services in Ecuador is safe, feasible and acceptable to users requesting a medication abortion and who are less than 12 weeks pregnant.

NCT ID: NCT06264349 Not yet recruiting - Pregnancy Clinical Trials

Women and Maternity: Development of a Nutritional Education Project

MATER
Start date: March 15, 2024
Phase: N/A
Study type: Interventional

The "first 1000 days of life", from conception to 2 years of life, are crucial for promoting the health of both mother and baby. During this period, a woman's diet and lifestyle play a significant role in determining the future health of the child. The perinatal period is an ideal time for regular contact with healthcare providers who can institute an intervention to encourage pregnant women to make nutritional changes to improve their health and that of their babies. Therefore, an educational program on an appropriate lifestyle during the "first 1000 days" can represent a crucial primary prevention strategy in reducing the risk of developing obesity and non-communicable diseases (NCDs) during childhood and later adulthood.

NCT ID: NCT06259097 Not yet recruiting - Pregnancy Clinical Trials

Different Medications to Induce Labor

Start date: May 2024
Phase: Phase 3
Study type: Interventional

This is a randomized controlled trial examining whether the use of misoprostol or pitocin, in combination with a foley catheter, is more effective at inducing labor in patients with a gravid BMI that is considered obese.

NCT ID: NCT06199154 Not yet recruiting - Pregnancy Clinical Trials

Induction of Labor in Morbidly Obese Patients

Start date: May 2024
Phase: Early Phase 1
Study type: Interventional

The goal of this randomized control trial is to compare different doses of Misoprostol (25 mcg vs 50 mcg) in induction of labor (IOL) in morbidly obese patients with BMI >40. It is known that morbid obesity is a risk factor for failed IOL and ultimately cesarean delivery (CD.) If the rates of vaginal delivery in this population can improve, then surgical morbidity can be reduced in these patients.

NCT ID: NCT06046703 Not yet recruiting - Pregnancy Clinical Trials

Diet Quality of Pregnant Women With a Strict Plant-based Diet Versus an Omnivorous Diet

Start date: January 1, 2025
Phase:
Study type: Observational

The goal of this observational study is to compare the nutritional intake among pregnant women with a strict plant-based diet versus an omnivorous diet. The main aim is to compare vitamin B12 intake. Participants will be asked to: - fill out a health questionnaire - fill out a three-day food diary - undergo blood sampling Researchers will compare pregnant women with a strict plant-based diet and pregnant women with an omnivorous diet to see if their nutritional intake is comparable.