Pregnancy Loss Clinical Trial
Official title:
Silent Intracellular Infections and Early Pregnancy Loss
Correlation between the presence of intracellular viruses/bacteria and the incidence of miscarriage during the first trimester of pregnancy.
In this study we will analyse chorionic villi derived from abortion during the first
trimester of pregnancy (spontaneous abortion vs voluntary pregnancy interruption), in order
to correlate the presence of infective viruses/bacteria and the incidence of miscarriage.
The first objective of this project will be to find the viral DNA of HPV, BK and JC
polyomaviruses and bacterial DNA of Chlamydia trachomatis, Ureaplasma parvum, Ureaplasma
urealyticum, Mycoplasma hominis in the aborted tissues collected from spontaneous abortions,
and to compare the prevalence of these DNAs to those derived from elective specimens.
Acronyms:
DNA: deoxyribonucleic acid HPV: human papillomavirus PCR: polymerase chain reaction HPyV:
human polyomavirus PBMC: peripheral blood mononucleated cell BKV: BK polyomavirus JCV: JC
polyomavirus
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