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Pregnancy Complications clinical trials

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NCT ID: NCT02866058 Completed - Cesarean Section Clinical Trials

Outcomes of Cesarean Section vs Vaginal Delivery: Instrumental Variable Adjusted Analysis

Start date: May 2011
Phase: N/A
Study type: Observational

This study will examine the effect of cesarean section on perinatal mortality, using data provided by the Canadian Institute for Health Information.

NCT ID: NCT02843984 Completed - Pregnancy Clinical Trials

Influence of Vaginal Lactoferrin on Amniotic Fluid Cytokines to Avoid Pregnancy Complications

Start date: March 2011
Phase: N/A
Study type: Interventional

Objective: To evaluate the influence of vaginal Lactoferrin administration on amniotic fluid concentration of 47 cytokines, chemokines and growth factors.

NCT ID: NCT02834897 Completed - Clinical trials for Pregnancy Complications

Performance Evaluation of System EOS Imaging in Pelvimetry Versus Pelvi-scanner

PELVI-EOS
Start date: May 2015
Phase: N/A
Study type: Interventional

The purpose of this study and demonstrate the reliability of EOS imaging system in the measurement of internal diameters of obstetrical pelvis versus "Goldstandard current "that is the pelviscanner.

NCT ID: NCT02693041 Completed - Preterm Birth Clinical Trials

Pregnancy Complications - A Probiotic Interventional Study

Start date: June 2012
Phase: N/A
Study type: Interventional

Investigators hypothesize that a) probiotics decrease the overall inflammatory state in the pregnant woman, especially in women with high risk pregnancies.

NCT ID: NCT02682212 Completed - Clinical trials for Pregnancy Complications

Obstetric Perineal Trauma and Physiotherapy

Start date: March 16, 2016
Phase: N/A
Study type: Interventional

The main objective is to investigate effects of perineal trauma at birth on women´s health and whether early physiotherapy improves pelvic floor strength. This will be achieved by an acknowledged/validated questionnaire sent electronically 6 weeks after first delivery. Women with symptomes of urinary incontinence according to the questionnaire will be offered participation in a single-blinded randomized intervention study to compare outcome after targeted physiotherapy with conventional advice and support. Intervention encompasses weekly pelvic floor training for 12 weeks. Pelvic strength will be measured and symptom information collected before and after intervention and 12 months postpartum in both groups. Pelvic floor problems after delivery are common and often persistent, including urinary/fecal incontinence, pelvic organ prolapse and sexual problems. Such symptoms reduce QoL and handicap women in multiple ways, physically, psychologically and socially. More knowledge of whether interventions and guidelines in this field can improve health and QoL is required.

NCT ID: NCT02664467 Completed - Depression Clinical Trials

Chronobiology, Sleep Related Risk Factors and Light Therapy in Perinatal Depression: the Life-ON Project

Start date: May 2016
Phase: N/A
Study type: Interventional

In a 3 years longitudinal, observational, multicentre study, about 500 women will be recruited and followed-up from early pregnancy (10-15 gestational week) until 12 months after delivery. The primary aim of the present study is to systematically explore and characterize risk factors for perinatal depression (PND) by prospective sleep assessment (using wrist actigraphy, polysomnography and various sleep questionnaires) and blood based analysis of potential markers during the perinatal period (Life-ON study). Secondary aims are to explore the relationship between specific genetic polymorphisms and PND (substudy Life-ON1), to investigate the effectiveness of BLT in treating PND (substudy Life-ON2) and to test whether a short term trial of BLT during pregnancy can prevent PND (substudy Life-ON3). The characterization of specific predictive and risk factors for PND may substantially contribute to improve preventive medical and social strategies for the affected women. The study results are expected to promote a better understanding of the relationship between sleep disorders and the development of PND and to confirm, in a large sample of women, the safety and efficacy of BLT both in prevention and treatment of PND.

NCT ID: NCT02577536 Completed - Pregnancy Clinical Trials

PregSource: Crowdsourcing to Understand Pregnancy

PregSource
Start date: September 25, 2017
Phase:
Study type: Observational [Patient Registry]

PregSource uses a crowd-sourcing approach, asking pregnant women to enter information regularly and directly about their pregnancies throughout gestation and the early infancy of their babies into online surveys and trackers via a website and/or mobile application ("app"). In exchange, participants can track their data over time, print out reports to share with their healthcare team, and see how they compare to other women. In addition, PregSource will provide participants with links to trusted, evidence-based information about pregnancy management, issues, and complications. More information is available at: https://pregsource.nih.gov

NCT ID: NCT02528890 Completed - Clinical trials for Streptococcus B Carrier State Complicating Pregnancy

Group B Streptococcal Carrier State Prevalence Among Arab Pregnant Women in Northern Israel District

GBS
Start date: September 2015
Phase: N/A
Study type: Observational

The incidence of early neonatal GBS (group B Streptococcus) infection in the Nazareth Hospital through the years 2006-2013 has been higher compared to the national average. On reviewing all the cases of infants with early GBS infection, revealed that some of these infants were born to mothers who are not included in any of the high-risk groups that need to have prophylactic antibiotic treatment before delivery. Therefore, the question was whether pregnant Arab women in the North district of Israel have a higher GBS carrier state rate than the general rate in Israel?

NCT ID: NCT02434380 Completed - Clinical trials for Pregnancy Complications

Effect of Vitamin D Replacement on Maternal and Neonatal Outcomes

Start date: July 2015
Phase: Phase 3
Study type: Interventional

The optimal vitamin D replacement dose during pregnancy remains undefined. Therefore, the aim of this study is to test the hypothesis that a daily equivalent dose of vitamin D of 3,000 IU/day is needed for Middle Eastern women, to optimize maternal vitamin D level and neonatal musculoskeletal parameters, specifically knee-heel length at birth and bone mineral content at one month of age.

NCT ID: NCT02362399 Completed - Clinical trials for Pregnancy Complication

Effect of Sildenafil Citrate on Uteri- Placental Perfusion, Doppler Indices in Growth Restricted Fetuses

Start date: March 2015
Phase: N/A
Study type: Interventional

To detect the effect of sildenafil citrate on Doppler parameters in fetuses suffering from growth restriction to support its use later as prolonged therapy in those pregnancies at higher risk for such complication.