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Pregestational Diabetes clinical trials

View clinical trials related to Pregestational Diabetes.

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NCT ID: NCT06141941 Recruiting - Clinical trials for Pregestational Diabetes

Does the Use of Continuous Glucose Monitoring (CGM) in the Immediate Postpartum Period in Women With Pregestational Diabetes Admitted to the Hospital Decrease Hypoglycemic Episodes

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

This study will examine whether continuous glucose monitoring in patients hospitalized in the immediate postpartum period is more effective than traditional point of care glucose testing in identifying patients with hypoglycemia.

NCT ID: NCT05553275 Completed - Clinical trials for Gestational Diabetes

Permissive Intrapartum Glucose Control

Start date: October 5, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to assess whether permissive intrapartum glycemic control compared to usual care would lead to similar rate of neonatal hypoglycemia among people with diabetes.

NCT ID: NCT05152589 Not yet recruiting - Hearing Loss Clinical Trials

Maternal Diabetes in Newborns With Hearing Loss

GDM
Start date: January 1, 2022
Phase:
Study type: Observational [Patient Registry]

This study aims to investigate the presence and characteristics of maternal diabetes as a risk factor in newborns with hearing loss. Hearing loss is one of the most common congenital anomalies among newborns. The newborn hearing screening program is important for early diagnosis in newborns with hearing loss.Gestational diabetes, on the other hand, is a metabolic disease that occurs during pregnancy and can cause complications as in other diabetes mellitus patients. Despite our knowledge of major complications, the effect of the hyperglycemic intrauterine environment on hearing outcomes has not been adequately studied. The inner ear does not store energy, so it has a particularly high sensitivity to altered blood sugar and insulin. Altered inner ear metabolism leads to auditory and balance disorders. There is no study in the literature comparing uncomplicated gestational diabetes and pregestational diabetes as a prenatal complication that poses a risk of hearing loss.

NCT ID: NCT03504592 Completed - Clinical trials for Gestational Diabetes

Smartphone Utilization for Glucose Monitoring and Antenatal Reporting

SUGAR
Start date: May 1, 2018
Phase: N/A
Study type: Interventional

This project will utilize MHealth technology to address the barriers providers and obstetric patients experience when reporting blood glucose results. Half of the participants will record their blood glucose values with the assistance of a smartphone device, the other half will continue in the traditional care method of the clinic.

NCT ID: NCT02793505 Completed - Pregnancy Clinical Trials

Safety of Metformin in Pregnancy

Start date: January 2014
Phase: N/A
Study type: Observational

This study aims to better characterize the risk linked to metformin use during pregnancy, using a prospective multicentric cohort design enabling a large sample size, in evaluating the rate of birth defects after first trimester exposure, as well as several other pregnancy related outcomes.

NCT ID: NCT01255384 Not yet recruiting - Clinical trials for Gestational Diabetes

Possible Epigenetic Changes in Offspring of Women With Pregestational and Gestational Diabetes

Start date: December 2010
Phase: N/A
Study type: Observational

Pregestational diabetes (PGD) during pregnancy may be associated with an increased rate of spontaneous abortions, intrauterine death and congenital anomalies among the offspring. Although the prevalence of congenital anomalies among the offspring of diabetic mothers is reduced as a result of the improvement of the glycemic control in the early pregnancy, the rate of congenital anomalies is increased and there seems to be an increased rate of neurodevelopmental disorders including some fine and gross motor deficits as well as increased rate of inattention and/or hyperactivity. In gestational diabetes, that develops in the second half of pregnancy (past the period of major organogenesis), there seems to be no increase in the rate of major congenital anomalies but there are some developmental disorders in the offspring. The exposure of the developing embryo and fetus to diabetic environment (i.e. hyperglycemia, hyperketonemia ext), is known to cause increased oxidative stress and significant changes in gene expression as observed in several experimental diabetic models. We hypothesize that diabetic environment may also cause long lasting epigenetic changes. It is therefore our purpose to evaluate these possible epigenetic changes and correlate their presence with the degree and time of onset of diabetes, (i.e. whether from the beginning as in PGD or in the second half of pregnancy as in GD), the degree of oxidative stress and with the neurodevelopmental outcome of the offspring. Diabetic pregnancies will be compared to a similar number of normal pregnancies in all parameters studied.

NCT ID: NCT01158040 Not yet recruiting - Clinical trials for Pregestational Diabetes

Intrapartum Maternal Glycemic Control Using Insulin Pump Versus Insulin Drip - Cohort Observational Trial

Start date: August 2010
Phase: N/A
Study type: Observational

The purpose of this study is to compare intrapartum glycemic control using insulin pump versus intravenous (IV) insulin administration.