Postprandial Efficacy of Probiotic Fruit Beverages on Glucose Tolerance and Insulin Resistance

Postprandial Hyperglycemia Clinical Trial

Official title:

Early Postprandial Efficacy of Probiotic Fruit Beverages on Glucose Tolerance and Insulin Resistance in Healthy Adults

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03159065
• Other study ID #: InVeg (1)
• Status: Completed
• Phase: N/A
• First received: May 17, 2017
• Last updated: May 18, 2017
• Start date: September 2014
• Est. completion date: January 2015

Study information

• Verified date: May 2017
• Source: Lund University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Consumption of polyphenol-rich fruits and vegetables may improve the postprandial glucose and insulin responses and hence promote well-being. It has previously been observed that consumption of a bilberry drink decreases the postprandial insulin demand. In the present study, the impact of probiotic fruit beverages with different polyphenol profiles on the postprandial levels of glucose and insulin, were investigated.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 12
• Est. completion date: January 2015
• Est. primary completion date: November 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Healthy, not on medication, non-allergic, individuals aged 18-65 years old, having a BMI between 20-30 kg/m2 and also maintaining stable body weight, i.e. less than 5% weight change in the last three months before the study.

Exclusion Criteria:

Related Conditions & MeSH terms

• Hyperglycemia
• Insulin Resistance
• Postprandial Hyperglycemia

Intervention

Other:
• Bilberry
Fruit beverage with bilberry and fermented oatmeal
• Blackcurrant
Fruit beverage with blackcurrant and fermented oatmeal
• Mango
Fruit beverage with mango and fermented oatmeal
• Beetroot
Fruit beverage with beetroot and fermented oatmeal
• Rose hip
Fruit beverage with rose hip and fermented oatmeal
• Glucose drink
A reference glucose drink

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Lund University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Efficacy of the study products on the postprandial serum insulin	The postprandial incremental area under the curve for serum insulin	Incremental area under the curve for serum insulin from 0 min up to 120 min following the ingestion of the study product
Secondary	Efficacy of the study products on the postprandial serum glucose	The postprandial incremental area under the curve for serum glucose	Incremental area under the curve for serum glucose from 0 min up to 120 min following the ingestion of the study product