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Postoperative Complications clinical trials

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NCT ID: NCT01389648 Completed - Abdominal Surgery Clinical Trials

Pre-operative Physiotherapy to Prevent Post-operative Complications

Start date: November 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the roll of pre-operative chest physiotherapy, in addition to the usual care given after major abdominal surgery, in the prevention of post-operative respiratory complications.

NCT ID: NCT01378559 Completed - Clinical trials for Postoperative Complications

Patient Satisfaction and Complications With the New Titan® One Touch Release (OTR) Penis Prosthesis

Start date: June 2011
Phase: N/A
Study type: Observational

The purpose of this study is to assess patient satisfaction with the Titan one touch release penis prosthesis and to register complications with this prosthesis. This will regard the first prostheses inserted at Herlev Hospital/Frederikssund Hospital. Patient satisfaction will be assessed by mailing out the "Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS) Questionnaire" and recording the patient answers. The most important question will be "Overall how satisfied are you with penile prosthesis?". Complications (including infection, bleeding, and mechanical failure) will be assessed by a patient chart review and confirmed by a brief phone interview.

NCT ID: NCT01373996 Completed - Atrial Fibrillation Clinical Trials

Clinical Investigation of Wireless Transmission of Invasive Blood Pressure Signal

Start date: June 2011
Phase: N/A
Study type: Observational

The purpose of this study is to determine whether wireless transmission of invasive arterial blood pressure signal (by HMW 10 Wireless System) from patient to patient's bedside monitor is feasible, safe and as accurate as conventional cable connection.

NCT ID: NCT01370798 Completed - Hypospadias Clinical Trials

Local Oestrogen Versus Placebo as Preoperative Treatment in Patients With Severe Hypospadias: Effects on Post-operative Complications

HYPOSPADES
Start date: May 26, 2011
Phase: Phase 3
Study type: Interventional

Hypospadias is a congenital abnormality of the penis that is caused by incomplete development of the anterior urethra. This pathology is one of the most common genital anomalies in paediatric urology .The incidence is reported to be 1 out of 250 live male births and is increasing regularly. The hypospadias surgeries present a high risk of post operative complications requiring re-interventions. A great part of the post operative complications is related to imperfect healing issues. If androgen stimulation seems to be deleterious, at the opposite, oestrogen could impact positively on the skin healing process. This point leads to the hypothesis that local transcutaneous oestrogen stimulation on the ventral and dorsal penile faces decreases the number of skin healing post-operative defects. The objective of the study is to assess the effect of oestrogen (applied once daily for 2 months prior to surgery) on the post-operative complications.

NCT ID: NCT01342900 Completed - Higk Risk Surgery Clinical Trials

Intraoperative Optimisation of Tissue Oxygenation

Start date: May 2011
Phase: N/A
Study type: Interventional

Monitoring and optimizing tissue oxygenation (StO2) in high-risk surgery and/or high-risk surgical patients may decrease the risk of postoperative complications. Tissue hypoxia occurs frequently during high-risk surgery in high-risk patients. The investigators want to see if an algorithm aimed at optimizing intraoperative tissue oxygenation reduces perioperative complications as well as length of stay in the intensive care unit (ICU LOS), 28-day mortality, and the duration of mechanical ventilation in these patients.

NCT ID: NCT01341002 Completed - Clinical trials for Postoperative Complications

Red Blood Cells (RBC) Transfusion Related to Central Venous O2 Saturation (ScvO2) Measurement

Start date: November 2009
Phase: N/A
Study type: Interventional

The objective of this study is to estimate red blood cells (RBC) transfusion related to central venous O2 saturation (ScvO2) measurement. This prospective, randomized trial is performed in visceral, vascular and thoracic surgery units in the university hospital of Lille. One hundred patients need to be included. Inclusion criteria are: age 18 to 99 year old, patient with central venous catheter in place and fulfilling the haemoglobin (Hb) threshold criteria for RBC transfusion according to the XXIIIth French Consensus Conference in critical care medicine recommendations. After randomisation, patients will be eligible to receive RBC according to their level of Hb in the standard group and according to the Hb and ScvO2 in the optimization group. Patients without any disease are transfused if their Hb level is below 7g/dL; patients older than 60 years or having sepsis are transfused if their Hb level is 8g/dL or lower and cardiac patients are transfused if their Hb level is 9g/dL or lower. In the second group, transfusion is performed if and only if the ScvO2 level is les than 70% when Hb is under the same threshold levels. The primary aim of the study is to compare the number of RBC units transfused by group (standard group or optimization group) over a period of 5 days counted from the first decision of transfusion taken post-operative. Considering the randomisation and considering the 50 % reduction of the decisions of transfusion in the group optimization, the absolute blood savings is estimated 25 % for the whole population. Secondary end points include the number of side effects associated with transfusion or when avoiding transfusion, length of hospital stay, and hospital mortality as well as major adverse events.

NCT ID: NCT01340742 Withdrawn - Clinical trials for Perioperative/Postoperative Complications

Remote Ischemic Preconditioning Before Abdominal Surgery

Start date: June 2010
Phase: N/A
Study type: Interventional

Major abdominal surgeries are associated with perioperative cardiac morbidity of up to 10%. Ischemic preconditioning may have a protective effect. The purpose of this study is to find out remote ischemic conditioning by inflating a blood pressure cuff on the arm will have a protective effect.

NCT ID: NCT01294930 Completed - Hip Fracture Clinical Trials

Indicators of Operative and Postoperative Complications in Patients Operated for Hip Fracture

IOPC
Start date: January 2011
Phase: N/A
Study type: Observational

Patients operated for hip fractures are older and have several conditions that have negative influences on the perioperative and postoperative prognosis. Hip fractures can also be painful, which is stressful for the physiology of the patient. Many old patients have received to little fluid intake. They often have diuretic therapy, which even worsens dehydration/hypovolemia. Some patients have to wait several days for surgery. Several studies have shown a high degree of complications and an increased mortality in this patient group. Early preoperative optimization can improve the outcome. The available methods for optimization of the patient are complicated and time consuming. The investigators wish with this study to try new approaches to find which patients still are dehydrated when they come to the operation ward. The aim is to measure the color and density of the urine as well as to register the the variability in the plethysmographic curve before spinal anaesthesia. These results will be compared to circulatory instability during and after surgery as well as to postoperative complications.

NCT ID: NCT01292343 Completed - Wound Infection Clinical Trials

Triclosan Toothpaste and Third Molar Surgery

Start date: February 2008
Phase: N/A
Study type: Interventional

Triclosan containing dentifrices are effective in the prevention of inflammatory complications following third molar surgery through reducing preoperative oral bacteria load.

NCT ID: NCT01268748 Unknown status - Pain, Postoperative Clinical Trials

Single Port Versus Four Ports Laparoscopic Cholecystectomy and Early Postoperative Pain

UMBI-CHOL
Start date: September 2010
Phase: N/A
Study type: Interventional

This is a trial to evaluate if single port laparoscopic cholecystectomy causes less pain than conventional laparoscopic cholecystectomy.