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Postoperative Complications clinical trials

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NCT ID: NCT02564133 Terminated - Hip Fractures Clinical Trials

Hip Fracture and Patent Foramen Ovale

COL-FOP
Start date: June 2013
Phase: N/A
Study type: Interventional

Ereth et al. showed in 1992, using transesophageal echocardiography, that the implantation of a hip prosthesis may be complicated by intracardiac embolization of various origin. A patent foramen ovale exists in approximately one fifth of the population; it facilitates the passage of embolus from the right heart to the left one and then especially to the coronary vessels and to the brain. The hypothesis supported in this research is that the prevalence of postoperative complications, especially neurological ones, is increased after surgery for hip fracture when patients have a patent foramen ovale.

NCT ID: NCT02461433 Terminated - Obesity Clinical Trials

Surgical Application of Vac Dressings In Obese Patients to Reduce Wound Complications

SAVIOR
Start date: June 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether application of an incisional wound Prevena trademark (TM) dressing (applies negative pressure to wounds) in the obese (BMI ≥30) surgical patient will reduce surgical site infections (SSI) when compared to the standard of care dressing.

NCT ID: NCT02453828 Terminated - Clinical trials for Postoperative Complications

Intraoperative Anesthesia Care Transition Checklist

Start date: June 2015
Phase: N/A
Study type: Interventional

Perioperative management decisions must often be made quickly and rely on practitioners having relevant facts at hand. During transitions of patient care between anesthesia providers, known as "handovers," information may not be completely or faithfully communicated, consequently impairing the provider's ability to intervene correctly in response to subsequent events. Checklists have consistently proven to be effective at enhancing communications during handovers, but whether anesthesia checklists improve patient outcomes has yet to be proven. The investigators propose to randomize intraoperative anesthesia provider handovers to standard practice (no specific format) or to a handover checklist presented by a decision-support system in conjunction with the investigators electronic record. Specifically, the investigators will test the hypothesis that incorporating a largely pre-populated handover checklist into transitions of intraoperative anesthesia care decreases a composite of mortality and serious cardiovascular, respiratory, gastrointestinal, urinary, and infectious complications.

NCT ID: NCT02323776 Terminated - Esophageal Cancer Clinical Trials

Defining the Radiotherapy Dose and Volume Parameters Affecting Postoperative Complications in Esophageal Cancer Patients

Start date: December 2014
Phase: N/A
Study type: Observational

The purpose of this study is to identify features of the cumulative dose-volume histogram (DVH) for patients treated with trimodality therapy in oesophageal cancer and correlate these with postoperative complications.

NCT ID: NCT02162810 Terminated - Hypospadias Clinical Trials

Effect of Steroids on Post-Operative Complications Following Proximal Hypospadias Repair

Start date: May 2014
Phase: N/A
Study type: Interventional

The primary objective of this study is to determine the efficacy of administering a course of postoperative oral steroids in pediatric patients undergoing proximal hypospadias repair as prevention against complications. Specifically, the study aims to assess if the steroids i) decrease the incidence of wound breakdown, fistula formation, stenosis or stricture formation, and the need for subsequent redo-hypospadias surgeries and/or fistula repairs and ii) improve the quality of wound healing including the overall cosmetic appearance of the phallus (i.e. location of the urethral meatus).

NCT ID: NCT02062788 Terminated - Insulin Resistance Clinical Trials

Evaluation of Preoperative Oral Rehydration Solution in Colectomy

Start date: February 2014
Phase: Phase 3
Study type: Interventional

Elective colectomy procedures typically require bowel preparation starting 2 days prior to the surgery. Osmotic laxatives such as Colyte® are administered 2 days prior, and Nothing by mouth (NPO) is required 1 day prior to ensure no fecal residue is left in the bowel. Though it may ensure a cleaner and safer surgery, this longer period of starvation increases insulin resistance and may increase post-op complications. However, there is evidence that administration of oral rehydration solution(ORS) prior to surgery reduces insulin resistance. Our purpose is to evaluate the difference of insulin resistance in those who received ORS 1 day prior to surgery and those who did not.

NCT ID: NCT01990287 Terminated - Low Back Pain Clinical Trials

SENSE (Subcutaneous and Epidural Neuromodulation System Evaluation) Study

SENSE
Start date: November 2013
Phase: N/A
Study type: Interventional

The purpose of the study is to demonstrate safety and efficacy of spinal cord stimulation with peripheral nerve field stimulation for the treatment of chronic low back and leg pain.

NCT ID: NCT01818297 Terminated - Clinical trials for Failed Back Surgery Syndrome

Subcutaneous Nerve Stimulation for Failed Back Surgery Syndrome (FBSS) Patients

SubQStim
Start date: April 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the safety and efficacy of Subcutaneous Nerve Stimulation (SQS) (also known as Peripheral Nerve Stimulation [PNS]) in the reduction of chronic, intractable post-surgical back pain in adults.

NCT ID: NCT01649505 Terminated - Breast Cancer Clinical Trials

Fibrin Sealant in Preventing Fluid Build Up During Surgery in Patients Undergoing Breast Reconstruction

Start date: January 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the efficacy of an alternative surgical technique and the use of fibrin sealant in preventing post-operative seroma formation. A seroma is a build-up of clear bodily fluids in a place on the body where tissue has been removed by surgery. Seromas can happen after breast surgeries. Seromas can appear about 7 to 10 days after surgery, after the drainage tubes have been removed. The breast area involved in the surgery may have a spot that's swollen and feels like there is liquid under the skin

NCT ID: NCT01473446 Terminated - Clinical trials for Postoperative Complications

Traditional Versus Goal Directed Perioperative Fluid Therapy in High Risk Patients

Start date: January 2012
Phase: N/A
Study type: Interventional

Is goal directed fluid therapy reducing postoperative complications in comparison to traditional fluid therapy for gastro surgical ASA III/IV patients? The investigators compare two groups of patients: one group receives goal directed fluid therapy guided by LiDCOrapid stroke volume variation (SVV), the other gets the "traditional" fluids, ie the current regime.