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Postoperative Complications clinical trials

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NCT ID: NCT00271167 Terminated - Heart Diseases Clinical Trials

A Trial of INO-1001 in Patients Undergoing Heart Surgery That Involves Heart-lung Bypass

Start date: October 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the safety of INO-1001, an intravenous PARP (poly-[ADP ribose] polymerase) inhibitor, in patients undergoing heart surgery. The study also measures whether INO-1001 reduces the side effects caused by heart-lung bypass machines.

NCT ID: NCT00260494 Terminated - Clinical trials for Postoperative Complications

Acupuncture and Post-Surgical Wound Healing

Start date: March 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if acupuncture improves wound healing. Since we, the investigators at the University of California, San Francisco (UCSF), know that how much oxygen is delivered to tissue is the best predictor of how well a wound will heal, we are measuring changes in tissue oxygen of wounds before and after acupuncture treatments. We are focusing on the leg wounds of coronary artery bypass graft (CABG) patients who have their saphenous veins harvested in an open fashion since this is a fairly well controlled patient model.

NCT ID: NCT00258453 Completed - Clinical trials for Brain and Central Nervous System Tumors

Observation of Young Patients Who Are Undergoing Surgery for Craniopharyngioma

Start date: May 2001
Phase: N/A
Study type: Interventional

RATIONALE: Collecting information on how craniopharyngioma is diagnosed and treated may help doctors predict a patient's response to treatment and help plan the best treatment. It may also help identify the intermediate- and long-term effects of treatment. PURPOSE: This clinical trial is collecting information on diagnosis, treatment, and quality of life of young patients who are undergoing surgery for craniopharyngioma.

NCT ID: NCT00247338 Completed - Clinical trials for Postoperative Complications

The Impact of Low Calorie and Low Nitrogen Parenteral Nutrition Support on the Clinical Outcome of Postoperative Patients

Start date: April 2005
Phase: Phase 4
Study type: Interventional

The study is designed to investigate the influence of parenteral nutrition (PN) with low nitrogen and calorie supply on the clinical outcome of patients after an operation compared to that of traditional PNs.

NCT ID: NCT00198523 Completed - Clinical trials for Postoperative Complications

A Bioequivalence Study of Tobramycin and Prednisolone Acetate Compared to PredForte

Start date: July 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate the bioequivalence of the combination test agent, prednisolone acetate 1.0% and tobramycin 0.3% ophthalmic suspension compared to PredForte (prednisolone acetate 1.0%) ophthalmic suspension. Bioequivalence will be measured by comparing aqueous humor concentrations of prednisolone acetate.

NCT ID: NCT00198445 Completed - Cataract Clinical Trials

Safety and Efficacy Study of Topical Bromfenac Versus Placebo to Treat Ocular Inflammation After Cataract Surgery

Start date: May 2003
Phase: Phase 3
Study type: Interventional

The primary objective of this study was to investigate the efficacy of bromfenac sodium ophthalmic solution 0.09% for treatment of post-operative ocular inflammation in subjects who undergo cataract extraction and intraocular lens implantation. The secondary objective was to investigate the safety and tolerability of the same.

NCT ID: NCT00182884 Completed - Clinical trials for Postoperative Complications

Donepezil in Preventing Delirium in Hospitalized Elderly

Start date: July 2004
Phase: Phase 4
Study type: Interventional

The purpose of this study is to explore the efficacy of a perioperative daily dose of Donepezil (a cholinergic enhancer) in reducing the incidence and severity of delirium.

NCT ID: NCT00182845 Completed - Clinical trials for Postoperative Complications

Donepezil in the Prevention of Post-Operative Cognitive Decline

Start date: February 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the feasibility of using Donepezil to prevent post-operative cognitive decline (POCD) among individuals aged 65 and older who have a baseline mild cognitive impairment (MCI) and are undergoing elective hip or knee replacement.

NCT ID: NCT00159185 Completed - Quality of Life Clinical Trials

Epidemiology Study in Major Orthopaedic Surgery

Start date: January 2004
Phase: N/A
Study type: Observational

The purpose of this study is to: - Create a database including a description of the patient population that undergoes total hip replacement with special emphasis on orthopedic and cardiovascular complications and the quality of life 1 year postoperatively. - Characterise the patient at risk for the above mentioned events - Create methods for predicting patients at risk for short-term (90 days) and long term (1 year) complications in relation to hip replacement surgery.

NCT ID: NCT00151307 Terminated - Clinical trials for Cardiovascular Diseases

Effects of Cerebral Oxygen Saturation on Neuropsychological Outcomes

Start date: February 2001
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effects of maintaining adequate cerebral oxygen saturation (over 40%) on patients undergoing cardiac surgery. Effects on neuropsychological outcome, length of ICU stay, and length of hospital stay will be measured.