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Relationship Between Acute Phase Markers and Post-operative Pain in Laparoscopic Cholecystectomy: An Observational Study

Post Operative Pain Clinical Trial

Official title:
Relationship Between Acute Phase Markers and Acute Post-operative Pain in Laparoscopic Cholecystectomy: An Observational Study

Clinical Trial Summary

Many patients undergoing laparoscopic cholecystectomy are prone to developing acute and chronic post-operative pain. The aim of the study is to show a possible correlation between pain and acute phase proteins in order to: - predict the severity of pain; - select most suitable pain relief therapy for the patient.

Clinical Trial Description

The day after surgery, some serum markers are determined by a blood sample. The markers analyzed are: - Leukocytes; - C-reactive protein (CRP); - D-dimer; - Fibrinogen; - Neutrophil-to-Lymphocyte Ratio (NLR). Pain level is assessed using the NRS scale at different times: - 1st post-operative day; - 7th post-operative day; - One month after surgery; - Three months after surgery; - Six months after surgery. Other data collected for the study are: gender, age, BMI. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06375057
Study type Observational
Source University of Roma La Sapienza
Contact Augusto Lauro
Phone +39 338 8663 879
Email augusto.lauro@uniroma1.it
Status Recruiting
Phase
Start date March 3, 2023
Completion date December 31, 2025
View Details
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