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Effects of Perioperative Intravenous Dexamethasone on Pain in Out Patient Knee Surgery

Post Operative Pain Clinical Trial

Official title:
Effects of Perioperative Intravenous Dexamethasone on Pain in Out Patient Knee Surgery

Clinical Trial Summary

The purpose of the study is to determine the opiate sparing effects of intravenously administered dexamethasone in outpatient knee surgery. Dexamethasone is a glucocorticoid with well known antiemetic effects. However, the analgesic effects of dexamethasone have not been adequately researched. Following surgery, patients are typically discharged home with PO opiates to manage post-operative pain. The investigators believe that by using VAS (Visual Analog Scale) for Pain the investigators can show that a single dose of dexamethasone can reduce pain scales and opiate consumption post-operatively, on Post Operative Day (POD 1) when compared to placebo.

Clinical Trial Description

Findings of Modest improvement in pain scores and postoperative nausea at 24 hours with Dexamethasone ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01149616
Study type Interventional
Source Beth Israel Deaconess Medical Center
Contact
Status Terminated
Phase Phase 4
Start date December 2009
Completion date December 2012
View Details
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