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Post-Op Complication clinical trials

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NCT ID: NCT06063538 Recruiting - Atrial Fibrillation Clinical Trials

Prevention of Postoperative Atrial Fibrillation (POAF) Using Intra-Pericardial Amiodarone

Start date: February 15, 2024
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to evaluate the combination of CardiaMend, with the addition of amiodarone in the prevention of postoperative atrial fibrillation (POAF) in patients undergoing cardiac arterial bypass grafting (CABG) or valve surgery.

NCT ID: NCT06050551 Recruiting - Clinical trials for Post-Op Complication

Pigtail or Chest Tube Placement After Uniportal Video-assisted Thoracoscopic Surgery

Start date: March 8, 2023
Phase: N/A
Study type: Interventional

This study aims to figure out how small-bore pigtail catheter or large-bore chest tube for postoperative drainage impact on analgesic efficacy and actually enhance recovery postoperatively.

NCT ID: NCT05861089 Recruiting - Clinical trials for Post-Op Complication

Rest PETCO2 as a Predictor of Post-operative Complications

Start date: June 1, 2023
Phase:
Study type: Observational

Cardiopulmonary exercise testing (CPET) is considered to be a golden standard in preoperative risk assessment and stratification of high risk patients scheduled for major surgery. However, not all of the patients requiring surgery are willing or able to complete this type of testing. Vascular surgery patients are predominantly elderly people, with significant comorbidity and high degree of frailty and often can not undergo CPET. In recent years, new parameters with similar prognostic value as standard CPET parameters were studied. Specifically, the partial pressure of end-tidal carbon dioxide (PETCO2) at rest has been shown to have the same prognostic value as ventilatory efficiency. We hypothesized low PETCO2 at rest will be associated with the development of pulmonary and cardiovascular post-operative complications in patients after major vascular surgery. Accordingly, our aim is to compare PETCO2 measured at rest before surgery in patients who develop post-operative complications and in those who do not.

NCT ID: NCT05710913 Recruiting - Clinical trials for Diabetes Mellitus, Type 2

Development of Machine Learning Models for the Prediction of BMI and Complications After Bariatric Surgery (CABS-Study)

Start date: January 5, 2023
Phase:
Study type: Observational

This Study aims to develop machine learning models with the ability to predict patients' BMI and complications after Bariatric Surgery (CABS-Score). This Study also aims to develop machine learning models with the ability to predict diabetic (DM II)patients' remission rate after Bariatric Surgery. The service mentioned above will be publicly available as a web-based application

NCT ID: NCT05368233 Recruiting - Emergencies Clinical Trials

Impact of Abdominal Drains on the ERAS Pathway in Peptic Perforation

TUBELESS
Start date: June 15, 2022
Phase: N/A
Study type: Interventional

This study plans to assess the effect of placement of abdominal drains on the outcomes of ERAS (Enhanced recovery after surgery) protocol in the perioperative management of peptic perforation. In the study arm ERAS protocol will be implemented avoiding use of abdominal drain. In the control arm abdominal drains will be placed in the early post operative period while using the ERAS protocol. The effect of drains on duration of post operative stay and other return to physiological parameter like onset of ambulation, oral intake, passing flatus and feces etc. will be studied. The investigators hypothesize that the non-placement of abdominal drain postoperatively will not have worse outcomes than in cases where it is used postoperatively, in terms of length of hospital stay. .

NCT ID: NCT05269368 Recruiting - Clinical trials for Post-Op Complication

Interest of Wicking for Ossicular Surgery and Myringoplasty

MECH-ORL
Start date: May 16, 2022
Phase: N/A
Study type: Interventional

Myringoplasties and ossicular surgery are very common procedures. Following these otological surgeries, most surgeons install a wicking. This intervention consists of placing a wick, absorbable or not, in the external acoustic meatus, after having replaced the tympanomeatal flap.

NCT ID: NCT05242328 Recruiting - Post-operative Pain Clinical Trials

Postoperative Analgesia y After Uniportal Video-assisted Thoracoscopic Surgery

Start date: January 5, 2021
Phase: N/A
Study type: Interventional

Ultrasound-guided erector spinae plane block (ESPB) is an interfascial blockade during thoracic anesthesia, first described by Forero in 2016, and is highlighted by technically feasibility and less complication rate. The patient is placed as decubitus position. The anesthesiologists use echo to identify the ipsilateral transverse process at T5 level, and insert the needle to 2-3 cm lateral to the spinous process until contact the transverse process. Then the injected local anesthetic will penetrate via erector spinae muscle to paravertebral space to affect and relieve pain.

NCT ID: NCT04915261 Recruiting - Clinical trials for Post-Op Complication

A Randomized Trial of Lenient Versus Strict Arm Instruction Post Cardiac Device Surgery

LENIENT
Start date: August 19, 2021
Phase: Phase 4
Study type: Interventional

The purpose and objectives of this study is to investigate whether reducing the existing arm restrictions on patients who receive Cardiac Implantable Electronic Devices (CIED) will result in an improved patient experience post operatively and reduce complication rates. There are multiple and varied arm restriction instructions given to patients receiving CIED's with limited universally accepted protocols or advice on restrictions for patients following surgery. Restrictions such as arm immobilization, showering and weight lifting, in addition to contradictory advice between various hospitals and physicians, can negatively affect patient quality of life and increase patient anxiety with no current evidence for benefit. A cluster cross over randomized trial has been designed to test the comparative effectiveness of lenient vs strict arm restrictions for all patients receiving implantable devices. Instructions within both arms of this study are considered within reasonable practice in Canada. All arm restriction instructions and parameters will be embedded within EPIC, nurses will teach the restriction in addition they will be provide to the patients via printed EPIC discharge summaries. Further links will be embedded in the After Visit Summary (AFS) printouts and my Chart for patients in EPIC. These instructions will be changed every 7 months, as per the crossover design of the trial. Additionally, both arms will utilize interactive voice recognition (IVR) to provide patients with further reminders and instruction on arm restrictions. All patients are given standard of care instructions for follow up and complication assessment through our device clinic and 24/7 on call nursing program.

NCT ID: NCT04908826 Recruiting - Choledocholithiasis Clinical Trials

Comparison of Icg's Route of Administration During Laparoscopic Cholecystectomy

Start date: January 3, 2022
Phase: N/A
Study type: Interventional

The aim of the trial is to compare the routes of administration of indocyanine green (ICG) during laparoscopic cholocystectomy.

NCT ID: NCT04826575 Recruiting - Lung Cancer Clinical Trials

Pre-habilitation in Lung Surgery Candidates

Start date: March 25, 2021
Phase: N/A
Study type: Interventional

We hypothesize that high intensity respiratory muscle training will improve ventilatory efficiency (VE/VCO2 slope) and will be associated with decreased PPC, decreased mortality and better quality of life in lung resection candidates. Accordingly, the aim of this study will be to compare rest and exercise ventilation and gas exchange parameters as well as postoperative complications, quality of life and mortality in patients who undergo high intensity respiratory muscle training compared to patients who receive the usual standard of care.