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Clinical Trial Summary

The purpose of this study is to evaluate the comparative effectiveness of nadroparin versus transjugular intrahepatic portosystemic shunt in cirrhotic patients with refractory asymptomatic portal vein thrombosis using a design of a multicenter, randomized controlled trial


Clinical Trial Description

This research project aims to investigate the efficacy and safety of anticoagulant therapy in patients with portal vein thrombosis (PVT) associated with liver cirrhosis. Building upon this, a randomized controlled study will be carried out for PVT patients with poor response to anticoagulant treatment. The study will compare the effects of transjugular intrahepatic portosystemic shunt (TIPS) and prolonged anticoagulant therapy. The ultimate goal is to provide high-quality clinical research evidence for interventional treatment of liver cirrhosis-associated PVT. This comprehensive approach aims to provide evidence-based medical guidance for optimizing the treatment pathway for refractory PVT in liver cirrhosis. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06319131
Study type Interventional
Source Shanghai Zhongshan Hospital
Contact Jie CHEN, MD
Phone 8613764633539
Email chen.jie5@zs-hospital.sh.cn
Status Not yet recruiting
Phase N/A
Start date May 1, 2024
Completion date May 30, 2026

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