Ocular Findings of Polycystic Ovary Syndrome

Polycystic Ovary Syndrome Clinical Trial

Official title:

Ocular Surface Disease Test Results, Corneal Biomechanical Properties, and Structural Parameters in Patients With Polycystic Ovary Syndrome

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03896841
• Other study ID #: 25801608
• Status: Completed
• Start date: March 17, 2013
• Est. completion date: March 30, 2018

Study information

• Verified date: January 2019
• Source: Istanbul Medeniyet University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Purpose: This study aimed to compare the ocular surface disease test results, anterior segment parameters, and ocular response analyzer (ORA) findings of polycystic ovary syndrome (PCOS) patients with those of healthy reproductive age female controls.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 38
• Est. completion date: March 30, 2018
• Est. primary completion date: March 20, 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 19 Years to 43 Years

Eligibility

Inclusion Criteria:

• premenopausal with PCOS

Exclusion Criteria:

• patients with external ocular disease other than dry eye complaints,

• use of topical drops that can affect the tear film layer,

• contact lens use histories,

• those who received hormone therapy for 6 months,

• those who have systemic medication or systemic disease that may affect the tear film layer and reproductive physiology,

• previous eye surgeries,

• smokers and alcohol users,

• those having diseases (Cushing's syndrome or androgen-secreting tumors) causing similar clinical findings.

Related Conditions & MeSH terms

• Polycystic Ovary Syndrome
• Syndrome

Intervention

Other:
• Observation
Ocular Findings Observations

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Istanbul Medeniyet University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Comparison of the anterior segment parameter results (Pentacam).	measurement of the central corneal thickness.	1 year
Primary	Comparison of the corneal biomechanical parameter results (ocular response analyzer).	measurement of the corneal hysteresis (CH).	1 year