Pneumonia Clinical Trial
Official title:
Role of Chest Ultrasound in Diagnosing and Follow-up of Pneumonia. Prospective Comparison Between X-ray Chest Film in Two Planes and "Low-dose" Spiral Computed Tomography
Verified date | August 2011 |
Source | University of Jena |
Contact | n/a |
Is FDA regulated | No |
Health authority | Germany: Ethics CommissionAustria: Ethikkommission |
Study type | Observational |
The study of a large number of patients (at least 200 patients) from several European
centres aims to investigate the value of chest ultrasound in diagnosing and checking the
course of pneumonia as compared to a chest X-ray film in two planes and - in case of a
controversial X-ray finding- as compared to low-dose CT.
An X-ray finding is regarded controversial, if infiltrates cannot be reliably excluded or
not reliably represented and if a definite diagnosis is, thus, not possible. A low-dose CT
is indicated even in case of a positive chest ultrasound and negative X-ray finding.
Sonographic recording and characterization of pneumonic infiltrates is performed both at the
time of diagnosing and in the further course under therapy.
Status | Completed |
Enrollment | 397 |
Est. completion date | February 2011 |
Est. primary completion date | February 2011 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: Patients with clinically suspected CAP who received no antibiotic treatment yet - Patients in whom a chest X-ray in 2 planes was already performed, can be included in the study, if chest ultrasound is performed within 24 hours after X-ray and if the X-ray finding is neither available to nor known to the examiner doing the ultrasound examination. - Age > 18 years - Patient's declaration of consent is available. Exclusion Criteria: - Patients with HAP - Age <18 years - Patients in whom the time difference between chest ultrasound and chest X-ray in 2 planes is more than 24 hours - Patients whose X-ray findings are with the examiner doing the ultrasound or are known to him - Pregnancy and lactation - Missing declaration of consent by the patient. |
Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Germany | Pneumology, Friedrich-Schiller University Jena | Jena | Thüringen |
Lead Sponsor | Collaborator |
---|---|
University of Jena |
Germany,
Copetti R, Cattarossi L. Ultrasound diagnosis of pneumonia in children. Radiol Med. 2008 Mar;113(2):190-8. doi: 10.1007/s11547-008-0247-8. Epub 2008 Apr 2. English, Italian. — View Citation
Reissig A, Kroegel C. Sonographic diagnosis and follow-up of pneumonia: a prospective study. Respiration. 2007;74(5):537-47. Epub 2007 Feb 27. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | sensitivity of chest ultrasound in diagnosing pneumonia | baseline diagnostic | No | |
Secondary | Specificity | baseline diagnostic | No |
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