Clinical Trial Details
— Status: Enrolling by invitation
Administrative data
| NCT number |
NCT05461989 |
| Other study ID # |
GO 22/505 |
| Secondary ID |
|
| Status |
Enrolling by invitation |
| Phase |
|
| First received |
|
| Last updated |
|
| Start date |
September 30, 2022 |
| Est. completion date |
August 30, 2025 |
Study information
| Verified date |
April 2024 |
| Source |
Hacettepe University |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Observational [Patient Registry]
|
Clinical Trial Summary
One of the most prevalent chronic disorders in children, especially teenagers, is
hypertension . The prevalence of hypertension has significantly increased in recent years,
particularly with the rise in obesity. It has been demonstrated that hypertension is a
significant, controllable risk factor for cardiovascular disease and that it is linked to
atherosclerosis in children. Additionally, in patients with hypertension who were monitored
from infancy to adulthood, it was discovered that the unfavorable cardiac alterations and
vascular damage linked to hypertension were linked to early cardiovascular disease in adults.
Therefore, the key to preventing cardiovascular disease in children and
adolescents-especially when risk factors like obesity, diabetes, or chronic renal disease are
present-is early diagnosis and effective treatment of hypertension. Insufficient exercise and
sedentary lifestyles are additional risk factors for pediatric hypertension.Investigating
physical activity barrier in teenage hypertension patients is vital in light of all these
factors as well as studies on adolescents' inadequate physical activity. The literature is
lacking studies examining the obstacles to physical exercise faced by people with adolescent
hypertension, hence this topic is open for investigation.
Description:
One of the most prevalent chronic disorders in children, especially teenagers, is
hypertension . The prevalence of hypertension has significantly increased in recent years,
particularly with the rise in obesity . Primary hypertension, also known as essential
hypertension, which was once thought to be an adult condition, is becoming more prevalent in
the pediatric population, partly because of the obesity pandemic . Children who are obese
have a three times higher risk of developing hypertension than children who are not obese .
Based on the etiology, hypertension can be divided into two types: primary or essential
hypertension, which has no known cause, and secondary hypertension, which has a known cause.
Stage I (mild) hypertension is the most common symptom of primary hypertension, which is also
linked to a favorable family history . Very young children, those with stage II hypertension,
and those with clinical signs suggesting systemic disorders linked to hypertension should all
be evaluated for secondary hypertension. An underlying vascular, neurological, endocrine, or
renal parenchymal illness may cause secondary hypertension .
It has been demonstrated that hypertension is a significant, controllable risk factor for
cardiovascular disease and that it is linked to atherosclerosis in children. Additionally, in
patients with hypertension who were monitored from infancy to adulthood, it was discovered
that the unfavorable cardiac alterations and vascular damage linked to hypertension were
linked to early cardiovascular disease in adults.Therefore, the key to preventing
cardiovascular disease in children and adolescents-especially when risk factors like obesity,
diabetes, or chronic renal disease are present-is early diagnosis and effective treatment of
hypertension.
Insufficient exercise and sedentary lifestyles are additional risk factors for pediatric
hypertension. Low levels of physical activity and hypertension have a continuous, temporal,
and independent association, according to epidemiological research . According to data, 80%
of kids and teenagers in 105 countries do not engage in the recommended amount of physical
exercise, which is at least 60 minutes of moderate to strenuous activity per
day.Additionally, many kids and teenagers engage in sedentary activities for more than 4
hours per day, even though less than 2 hours per day are advised for screen-based
entertainment (such as watching TV, using a computer, and playing video games). According to
research, children and adolescents who watch television or spend too much time on screens had
lower fitness levels, worse self-esteem, less prosocial behavior, and higher systolic and
diastolic blood pressure. Prospective research regularly demonstrates that exercise shields
adults from high blood pressure. Physical activity has been dubbed a "poly-drug" for its
preventive and therapeutic effects in reducing the global health burden of cardiovascular
disease, increasing physiological function, and slowing cardiovascular aging.Investigating
physical activity barrier in teenage hypertension patients is vital in light of all these
factors as well as studies on adolescents' inadequate physical activity. The literature is
lacking studies examining the obstacles to physical exercise faced by people with adolescent
hypertension, hence this topic is open for investigation.
