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Mitochondrial Capacity in Pregnant Women — Mito Moms  

Physical Activity Clinical Trial

Official title:
The Effect of Physical Activity on in Vivo and in Vitro Mitochondrial Capacity in Pregnant Women

Clinical Trial Summary

This Pilot & Feasibility study will test the hypothesis that pregnant women who are more active will have better functioning mitochondria in vivo (higher ATPmax, via 31P-MRS), which will be positively related to maternal and infant mitochondrial function in vitro (higher oxygen consumption rates in primary myotubes and umbilical cord derived mesenchymal stem cells, respectively). Twenty pregnant women (10 active and 10 sedentary) will be recruited in the first trimester of pregnancy determined from self-reported physical activity and assessment by activity monitors. Placental biospecimens will be collected during delivery for other molecular mitochondrial analyses.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03489564
Study type Observational
Source Pennington Biomedical Research Center
Contact
Status Completed
Phase
Start date March 19, 2018
Completion date February 11, 2020
View Details
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