Physical Activity and Its Impact on Colon Cancer Surgery

Physical Activity Clinical Trial

— PACOS  

Official title:

Physical Activity and Its Impact on Colon Cancer Surgery: Clinical and Histological Effects

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03947840
• Other study ID #: PACOS
• Status: Completed
• Start date: January 30, 2019
• Est. completion date: February 20, 2024

Study information

• Verified date: February 2024
• Source: Umeå University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

This is a prospective clinical study that studies how the physical activity level before operation of colon cancer affects the outcome of complication and histology. The hypothesis is that patients who are more physical active have less postoperative complications and different histological immunological response around the tumor. The investigators are testing the patients before the surgery with physical tests for fitness, strength and physical activity level. Questionnaires are also filled by the patients for pain, anxiety, depression and motivation for life style changes. Their body mass is analyzed with a DEXA (Dual-energy X-ray absorptiometry scan). For one years the investigators are monitoring their activity and follow up for physical tests, DEXA and questionnaires is at 6 and 12 months. The histology is analyzed after surgery to se if there is a different immunological response around the tumor.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 85
• Est. completion date: February 20, 2024
• Est. primary completion date: February 20, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• 18 years.
• Colon cancer which is going to surgery

Exclusion Criteria:

• Not able to do physical tests
• Severe disease that makes a risk to do tests.
• Not able to make informed consent due to psychic disease or dementia

Related Conditions & MeSH terms

• Colon Cancer
• Colonic Neoplasms
• Physical Activity

Intervention

Behavioral:
• Physical activity
Se their physical activity level

Locations

Country	Name	City	State
Sweden	Region Vasterbotten, centre of surgery	Umeå	Vasterbotten

Sponsors (2)

Lead Sponsor	Collaborator
Umeå University	Västerbotten County Council, Sweden

Country where clinical trial is conducted

Sweden, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of postoperative complications	To study if there are differences in postoperative complications in different active patients.	1 year
Primary	Rate of immunological response	To study if there is a difference in immunological reaction among physical active patients.	1 year
Secondary	Rate of recovery in physical activity	To study if physical active patients have a faster postoperative recovery	1 year