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Phobia, Social clinical trials

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NCT ID: NCT02036658 Completed - Clinical trials for Social Anxiety Disorder

Emotion Regulation During RCT of CBT vs. MBSR for Social Anxiety Disorder

Start date: March 2011
Phase: N/A
Study type: Interventional

The purpose of the study is to investigate the immediate and longer-term impact of Cognitive-Behavioral Group Therapy (CBGT) versus Mindfulness-Based Stress Reduction (MBSR) for patients with Social Anxiety Disorder.

NCT ID: NCT02028247 Completed - Autism Clinical Trials

Psychotherapy for Anxiety in Children With Autism Spectrum Disorder

TAASD
Start date: April 2014
Phase: N/A
Study type: Interventional

Anxiety disorders affect 40 to 50% of children with autism spectrum disorders (ASD), contributing to substantial distress and impairment. The goal of this study is to examine the effectiveness of a personalized type of psychotherapy against standard-care psychotherapy for addressing anxiety in youth with ASD.

NCT ID: NCT01947647 Completed - Clinical trials for Major Depressive Disorder

Transdiagnostic Psychotherapy for Veterans With Mood and Anxiety Disorders

TBT-RCT
Start date: November 17, 2014
Phase: N/A
Study type: Interventional

Cognitive behavioral therapy (CBT) is a brief, efficient, and effective psychotherapy for individuals with depressive and anxiety disorders. However, CBT is largely underutilized within Veteran Affairs Medical Centers (VAMCs) due to the cost and burden of trainings necessary to deliver the large number of CBT protocols. Transdiagnostic CBT, in contrast, is specifically designed to address numerous distinct disorders within a single protocol. This transdiagnostic approach has the potential to dramatically improve the accessibility of CBT within VAMCs and therefore improve clinical outcomes of Veterans. The proposed research seeks to evaluate the efficacy of a transdiagnostic CBT by assessing clinical outcomes and quality of life in VAMC patients with depressive and anxiety disorders throughout the course of treatment and in comparison to an existing evidence-based psychotherapy, behavioral activation treatment.

NCT ID: NCT01919970 Completed - Autism Clinical Trials

Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety

Start date: August 2013
Phase: N/A
Study type: Interventional

Autism spectrum disorders affect as many as 1 out of 88 children and are related to significant impairment in social, adaptive, and school functioning. Co-occurring conditions, such as anxiety, are common and may cause substantial distress and impairment beyond that caused by the autism diagnosis. Accordingly, we are proposing a randomized controlled trial to examine the effectiveness of a form of cognitive-behavioral therapy relative to treatment as usual (TAU) in 50 youth ages 6-12 with autism spectrum disorders and comorbid anxiety.

NCT ID: NCT01900301 Completed - Clinical trials for Social Anxiety Disorder

Generalization of Extinction Learning

Start date: August 2013
Phase: Phase 1
Study type: Interventional

Fear, whether it occurs in humans suffering from an anxiety disorder or in experimental models with rodents, is reduced by exposing the frightened organism to the fearful stimulus in the absence of any negative consequences (i.e., extinction, or exposure therapy). However, fear often renews when the feared stimulus is encountered in a context different from the exposure context. In rats, the investigators found that interfering with the animal's ability to process contexts during extinction by administering an anticholinergic drug prevented fear renewal. This proposal will determine if the beneficial effect of this drug translates to exposure therapy in socially anxious humans. To this end, 100 individuals with Social Phobia who fear public speaking will undergo repeated sessions of exposure to public speaking, within a virtual reality context. Participants will be randomized to either drug placebo, .4mg/.01 mL Scopolamine, .5mg/.01 mL Scopolamine or .6mg/.01 mL Scopolamine, administered via nasal drops, prior to each session of exposure therapy. One month after completion of exposure therapy, context renewal will be tested by comparing physiological and subjective responses to public speaking in the same virtual context as used during exposure therapy versus a context different than the one used during exposure therapy. The goal is to identify the dose of Scopolamine associated with the greatest reduction in context renewal. In addition, a secondary analysis will attempt to identify those individuals who benefit most from Scopolamine-augmentation of exposure therapy.

NCT ID: NCT01856530 Completed - Clinical trials for Social Anxiety Disorder

Effect of Oxytocin Nasal Sprays on Social Behavior in Social Anxiety Disorder

Start date: July 2012
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to learn more about how the hormone, oxytocin, impacts social behavior in terms of cooperation with others, attention processing, and reward processing, among patients with social anxiety disorder. Based on available research, the investigators predict that in patients with social anxiety disorder, oxytocin will improve social cooperation during an online ball-tossing game called Cyberball, reduce attention toward socially threatening cues during a dot-probe task, and lead to greater willingness to work for monetary rewards for others rather than themselves during an effort expenditure task.

NCT ID: NCT01736631 Completed - Bipolar Disorder Clinical Trials

Cognitive Behavioural Therapy for Social Phobia in People With Bipolar Disorder

Start date: March 2013
Phase: N/A
Study type: Interventional

We are doing this study to find out how well cognitive behavioural therapy for social phobia works in people with bipolar disorder, who also have social phobia.

NCT ID: NCT01565629 Completed - Autism Clinical Trials

Computer- Assisted Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders

CCAL
Start date: February 2012
Phase: N/A
Study type: Interventional

This study will examine the efficacy of a computerized cognitive behavioral therapy (CCBT) program for children with anxiety and autism spectrum disorders.

NCT ID: NCT01557894 Completed - Phobia, Social Clinical Trials

Internet Treatment for Social Phobia in Romania

iSOFIE-Ro
Start date: April 2012
Phase: N/A
Study type: Interventional

The main aim of this study is to investigate the effectiveness of an Internet-delivered intervention for social phobia by comparing it to a waitlist control group. The second aim of the study is to track the potential changes in participants' thinking patterns. Because this is among the first guided Internet-delivered interventions conducted in Romania, the treatment credibility will also be investigated. Finally, the predictive power of anxiety sensitivity for both SAD symptoms and the treatment effectiveness will be investigated.

NCT ID: NCT01491880 Completed - Anxiety Disorders Clinical Trials

Treatment Study for Rural Latino Youth With Anxiety

Start date: November 2011
Phase: Phase 1/Phase 2
Study type: Interventional

This pilot study will examine the feasibility of two modes of service delivery (e.g., a minimal therapist contact, self-help program, and a more intensive therapist supported, telephone-based approach) in a rural, primarily Latino, population. These modes of delivery may ultimately improve access to evidence based treatments and mental health outcomes among underserved groups.