Periodontal Diseases Clinical Trial
Official title:
Treatment of Localized Advanced Periodontitis Using an Oscillating Chitosan Device Versus Regular Curettes Alone - a Randomized Parallel Arm Clinical Trial
40 patients diagnosed with localised periodontitis will be included at each center, 20 patients will be treated with the control treatment, 20 patients will be treated by test treatment.
2.3 This will be a prospective multicentre parallel arm randomized clinical trial of 6 months' duration. Clinical parameters of periodontal disease will be recorded at baseline and at 6 months. Radiographs will be taken at baseline and at 6 months.Treatment will be performed at baseline and thereafter every three months. 2.5 Study setting Patient screening, inclusions and all clinical examinations will be performed by a board-certified specialist in periodontology at the test centres. Treatment will be performed by a registered separate therapist, either dentist or dental hygienist. 2.7 Treatment allocation Patients will be allocated to one of the following treatments: control (curettes+ ultrasound scaler (USS) supra and subgingivally), test (curettes + USS supra and chitosan brush in oscillating handpiece subgingivally) by computer-generated block randomization to ensure equal sample sizes. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04712630 -
Non-Incised Papillae Surgical Approach (NIPSA) With and Without Graft
|
N/A | |
Recruiting |
NCT03997552 -
NIPSA Versus Marginal Approach by Palatal Incision and MIST in Periodontal Regeneration
|
N/A | |
Completed |
NCT04478864 -
Knowledge, Practice and State of Periodontal Health
|
||
Completed |
NCT03507868 -
YKL-40 and IL-6 Levels in Periodontal Disease
|
||
Completed |
NCT05720481 -
Impact of Periodontal Treatment on Growth Differentiation Factor-15 Levels
|
N/A | |
Recruiting |
NCT06052150 -
Oral Health In Cirrhosis of the Liver (ORACLE)
|
||
Recruiting |
NCT06025955 -
Evaluation of Outcomes of Minimally Invasive Non- Surgical Versus Surgical Therapy in Furcation Involvement.
|
N/A | |
Recruiting |
NCT03510702 -
SCREENING OF EPIGENETIC BIOMARKERS (miRNAs) IN THE GINGIVAL SULCUS
|
||
Completed |
NCT05631600 -
Manuka Honey as an Adjunct to Non-surgical Periodontal Therapy: Clinical Study
|
Phase 2/Phase 3 | |
Active, not recruiting |
NCT05068778 -
Development of an AI App to Improve Compliance in Periodontal Maintenance Patients
|
||
Not yet recruiting |
NCT05178563 -
Mechanisms of Acute Inflammation Following Periodontal Treatment
|
N/A | |
Recruiting |
NCT06086821 -
Clinical Relevance of Different Time of Periodontal Re-evaluation
|
N/A | |
Recruiting |
NCT06224699 -
Toothpaste With Sodium Carbonate in Patients With Gingivitis
|
N/A | |
Not yet recruiting |
NCT05721313 -
Vital Root Amputation in Molars With Advanced Periodontal Furcation Involvement: a Preliminary Study
|
N/A | |
Completed |
NCT06040944 -
Antipsychotic Induced Hyperprolactinemaia as Risk Factor for Periodontitis in Schizophrenic Patients
|
||
Completed |
NCT06306937 -
Serum Levels of Vitamin D and IL8 in Patients With Periodontitis
|
||
Recruiting |
NCT04669717 -
Antibiotics as Adjuncts to Periodontal Therapy:Pharmacokinetic Considerations and Dosing Strategies
|
Phase 4 | |
Completed |
NCT05576142 -
Oral Findings in Pediatric Patients With Allergic Rhinitis and/or Asthma
|
||
Not yet recruiting |
NCT03588507 -
Clinical and Radiographic Evaluation of PPF With or Without NCHA Bone in Treatment of Intrabony Defects
|
N/A | |
Completed |
NCT03694496 -
The Effectiveness of an Oral Health Education Programme of Adolescents in Hong Kong
|
N/A |