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YKL-40 and IL-6 Levels in Periodontal Disease

Periodontal Diseases Clinical Trial

Official title:
Effect of Non-Surgical Periodontal Therapy on Salivary and Gingival Crevicular Fluid YKL-40 and IL-6 Levels in Chronic Periodontitis

Clinical Trial Summary

The primer aim of the study was to investigate saliva and gingival crevicular fluid (GCF) YKL-40 and also interleukin-6 (IL-6) levels in chronic periodontitis pathogenesis.

Clinical Trial Description

This study consisted of two groups: 26 periodontally healthy individuals and 26 generalized chronic periodontitis patients. Chronic periodontitis patients were received nonsurgical periodontal treatment. Clinical measurements were recorded, saliva and GCF samples were obtained before and at first and third months after periodontal therapy. Levels of YKL-40 and IL-6 in saliva and GCF were analyzed by enzyme-linked immunosorbent assay. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03507868
Study type Observational
Source Adnan Menderes University
Contact
Status Completed
Phase
Start date September 2016
Completion date January 2018
View Details
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