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Pediatrics clinical trials

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NCT ID: NCT05275881 Recruiting - Pain Clinical Trials

Impact of Virtual Reality in Pediatric Hematology and Oncology

Start date: October 13, 2022
Phase: N/A
Study type: Interventional

This pilot study will be testing the feasibility of medical hypnosis through virtual reality during invasive médical procédures in children with cancer. Patients age from 7 to under 18 years whose treatement protocols required a lumbure puncture and a chemotherapy by implantable venous access will be randomly assigned to virtual reality or treatement as usual (nitrous oxide, anxiolytics, opioid analgesics, psychotropic and benzodiazepine). We expect the same benefit by using VR as usual intervention.

NCT ID: NCT04969133 Recruiting - Analgesia Clinical Trials

TAP Block Versus Local Anesthesia Wound Infiltration for Postoperative Pain Relief After Appendicectomy in Children

PABLO
Start date: July 30, 2021
Phase: N/A
Study type: Interventional

When performing laparoscopic appendectomy in children, regional anesthetic techniques are rou-tinely used concomitantly with general anesthesia. These techniques include local infiltration of the trocar wounds or transverse abdominal plane block (TAP block). In 2018, a position paper of the European Society of Pediatric Anaesthesiology advised for TAP block over local infiltration of the trocar wounds. However, there is no randomized study comparing both techniques in children. The aim of this study is to compare morphine consumption during the first 24 postoperative hours in children undergoing laparoscopic appendectomy and randomly allocated to either local infiltration of the trocar wounds or TAP block.

NCT ID: NCT04902391 Recruiting - Mental Health Clinical Trials

A Patient-Partnered, Pan-Canadian, Comparative Effectiveness Evaluation of an Acute Pediatric Mental Health and Addiction Care Bundle

Start date: February 9, 2022
Phase: N/A
Study type: Interventional

The investigators will determine, in an 8-site, hybrid Type 1 cluster randomized effectiveness implementation trial, if an acute mental health care bundle, compared to standard care, improves wellbeing at 30 days in children and youth seeking emergency department care for mental health and substance use concerns.

NCT ID: NCT04830280 Recruiting - Pediatrics Clinical Trials

Effect Posterior QLB on Atelectasis

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

We aimed to investigate the effect of posterior quadratus lumborum block on postoperative atelectasis in inguinal hernia surgery in pediatric patients.

NCT ID: NCT04293107 Recruiting - Quality of Life Clinical Trials

Gastro-oesophageal Reflux and NeuroDisability (Cerebral Palsy) in CHILDren

GRANDCHILD
Start date: January 22, 2021
Phase:
Study type: Observational

This study assesses the content validity of the PGSQ for parents/carer of children with cerebral palsy and GORD, including features such as readability, face validity and acceptability for completion. This will be done via 6 interviews, with the PGSQ being altered as identified as required. Reliability (test-retest) of the adapted version of the PGSQ being assessed with a sample of 20 parents/carers.

NCT ID: NCT04201704 Recruiting - Critical Illness Clinical Trials

Effect of Giving Reduced Fluid in Children After Trauma

Start date: August 27, 2018
Phase: N/A
Study type: Interventional

This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid strategies are now in practice. For decades, trauma patients got high volumes of IV fluid. Recent studies in adults show that patients actually do better by giving less fluid. The investigators do not know if this is true in children and this study is designed to answer that question and provide guidelines for IV fluid management in children after trauma.

NCT ID: NCT03986021 Recruiting - Pediatrics Clinical Trials

Reproductive Axis Maturation in the Early Post-Menarchal Years

Start date: December 19, 2019
Phase:
Study type: Observational

Background: Most adult women with irregular periods of unknown cause report symptoms dating back to early adolescence. This study aims to learn how girls' periods change in the 2 years after their first period. We are also looking at girls who may have a condition called PCOS. This will help researchers learn what healthy puberty looks like and how they can spot signs of hormone problems early on. Objective: To learn how long it takes girls to develop regular menstrual cycles after their first period. Eligibility: Healthy girls ages 8-14 who either (1) haven't had their first period but show signs of puberty, such as breast development and hair in the genital area; or (2) had their first period in the past 6 months Girls at risk for PCOS age 8-14 who have a mom or sister with PCOS Girls with irregulat menstrual cycles age 11-17.5 To compare with the girls, we are looking at women >=18-34 years old with PCOS, Healthy women >= 18-34 years old without PCOS Design: Both parents or guardians must allow their daughter to participate. They must attend all study visits with her. Participants will first be screened by phone. Those who qualify will be screened in person. They will have a physical exam. They will give blood and urine samples. They will have an ultrasound of their abdomen. They will fill out questionnaires. They will sit in a BOD POD for 6 minutes: This is an egg- shaped machine that takes body measurements. They have the option to provide DNA samples. Participants will have sets of visits at home or at the clinic about every 6 months. The number of visits in each set will depend on their menstrual cycle. Then they will have a final visit. Visits will include repeats of the screening tests. There are additional parts that participants may choose to be involved in depending on how involved they want to be. At home, participants will collect their urine daily to measure hormones. They will keep a diary of their periods. Adults: Women with known PCOS will complete the same Screening Visit as the girls and will collect dried urine specimens at home for 8 weeks; The Healthy control women group will complete the same Screening Visit as the girls and collect dried urine specimens at home for 2 menstrual cycles.

NCT ID: NCT03939091 Recruiting - Ultrasonography Clinical Trials

Ultrasonographic Versus Renographic Parameters in Prediction of Early Success After Pyeloplasty in Children

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

To study the predictive value of ultrasonographic (USG) parameters in the form of anteroposterior diameter , calyceal dilatation , calyx-to-parenchyma ratio , renal length , renal width , pelvis-to-cortex ratio (PCR) and parenchymal thickness versus renographic parameters in the form of T1/2 , differential renal function (DRF) and Tissue tracer transit (TTT) for early detection of children at risk of recurrent obstruction post unilateral pyeloplasty.

NCT ID: NCT03931122 Recruiting - Child Clinical Trials

Comparison of Weight-based Versus External Ear-size Based Technique for Selection of Laryngeal Mask Airway in Pediatric Surgical Patients.

Start date: December 11, 2019
Phase: N/A
Study type: Interventional

Laryngeal Mask Airway (LMA) is widely used in pediatric surgical patients. The manufacturer recommends the size of LMA to be used in children should be based on actual body weight but this method has several limitations. To overcome these concerns, various alternatives have been tried by different researchers, one of them is external ear size for LMA size selection. Investigators therefore would like to know whether the external ear size based method can be used for LMA size selection in pediatric surgical patients in Pakistan.

NCT ID: NCT03790566 Recruiting - Pediatrics Clinical Trials

Erector Spinae Plane Block for Peri-operative Pain Management in Pediatric Open Pyeloplasty Cases

ESPPOP
Start date: February 20, 2019
Phase: N/A
Study type: Interventional

Regional anesthesia decreases the need for intravenous analgesia in the peri-operative period. Erector spinae plane (ESP) and transversus abdominus plane (TAP) blocks are two common regional anesthesia techniques shown to be effective in open abdominal surgeries. We aim to compare effectiveness of ESP block with TAP block for peri-operative analgesia in pediatric open pyeloplasty patients with a flank incision.