Parkinson's Disease Clinical Trial
Official title:
Effectiveness of Multimodal Exercise Program on Depression and Health-Related Quality of Life in Patients With Parkinson's Disease
Depression symptoms are common in Parkinson's Disease, it affects health-related quality of life. The evidence showed that exercise improved depression and HRQOL in PD patients. However, studies rarely considered the appropriate exercise program for PD patients, we want to find the best exercise program for PD patients.
Objective: Evaluate the effectiveness of a 8-week multimodal exercise program on depression
and HRQOL in PD Patients.
Methods: Single-blinded, randomized controlled trial, from March 2016 to January 2017.
Ninety-eight patients recruited to 2 groups: exercise group (n = 49) and control group (n =
49). The primary outcomes were depression and HRQOL; the secondary outcomes were activity of
daily living, motor ability, fatigue, sleep quality and anxiety. Data collection at baseline,
week 4 and 8 after intervention. Intervention were Multimodal Exercise Program, at least
three times (30 - 50 minutes per section) a week or 10-15 minutes per section every day to
accumulate 150 minutes a week for 8 weeks.
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