Capturing Parkinson's Disease Medication Side Effects During Daily Activities

Parkinson's Disease Clinical Trial

Official title:

Phase I Study: Monitoring Levodopa-Induced Dyskinesia Using Accelerometer & Gyroscope-based Motion Detection System

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01429207
• Other study ID #: 1R43NS071882-01A1
• Status: Completed
• Phase: N/A
• First received: September 2, 2011
• Last updated: June 28, 2012
• Start date: August 2011

Study information

• Verified date: June 2012
• Source: Great Lakes NeuroTechnologies Inc.
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

The purpose of the study is to test whether body-worn wireless motion sensors can measure dyskinesias (involuntary movements caused by medications) in individuals with Parkinson disease (PD) independent of voluntary activity being performed and other PD motor symptoms (e.g. tremor).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 15
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

• Clinical diagnosis of probable or definite idiopathic Parkinson Disease with motor fluctuations that include dyskinesias after taking their usual dose of levodopa/carbidopa

Exclusion Criteria:

• Antipsychotic medications (including quetiapine and clozapine)

• Coexisting neurologic disease such as stroke or dementia

• Lacking capacity for informed consent

• Residing in a nursing home

• comorbid non-neurologic illnesses that impacts the ability to perform the study tasks

• Implantable defibrillators

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Dyskinesia
• Dyskinesias
• Parkinson Disease
• Parkinson's Disease

Locations

Country	Name	City	State
United States	University of Rochester Medical Center	Rochester	New York

Sponsors (2)

Lead Sponsor	Collaborator
Great Lakes NeuroTechnologies Inc.	University of Rochester

Country where clinical trial is conducted

United States,