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Clinical Trial Summary

This clinical trial is designed to test the safety and tolerability of injecting ANPD001 cells that will mature into dopamine-producing cells into the brain of participants with Parkinson Disease. All participants will have ANPD001 cells manufactured from their own previously collected cells.


Clinical Trial Description

Participants will undergo a surgical implantation of cells that will mature into dopamine-producing neurons under general anesthesia into a part of the brain where dopamine production is decreased in patients with Parkinson Disease. The effect on Parkinson Disease symptoms, safety and tolerability, and cell survival are assessed for 5 years post-transplant (with MRI and PET imaging scans of the brain). Safety and tolerability are assessed annually for an additional 10 years via telephone call (total follow-up of 15 years) ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06344026
Study type Interventional
Source Aspen Neuroscience
Contact
Status Enrolling by invitation
Phase Phase 1
Start date January 23, 2024
Completion date April 30, 2030

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