Pancreas Neoplasms Clinical Trial
Official title:
Comparing of a 22G EUS Procore Fine Needle Biopsy Device and a 20G EUS Procore Fine Needle Biopsy Device for Solid Pancreatic Lesions: a Prospective Multi-center, Randomized, and Controlled Trial
The purpose of this study is to compare the diagnosis accuracy of 22G EUS Procore fine needle biopsy (FNB)device and 20G EUS Procore fine needle biopsy device for solid pancreatic lesions.
This is a single-blind, randomized, controlled trial. One thousand two hundred and twenty four patients with solid pancreatic lesions referred for EUS guided fine needle biopsy will be randomly assigned to 4 arms. For arm A1 which will be used with 22G EUS Procore fine needle biopsy device, the pass sequence is slow pull(SP)-modified wet suction technique(MWST)-slow pull(SP)-modified wet suction technique(MWST). For arm A2 with 22G EUS Procore fine needle biopsy device, the pass sequence is MWST-SP-MWST-SP. For arm B1 with 20G EUS Procore fine needle biopsy device, the pass sequence is SP-MWST-SP-MWST. For arm B2 with 20G EUS Procore fine needle biopsy device, the pass sequence is MWST-SP-MWST-SP. All procedures will be performed by experienced echoendoscopists, and the patients and assessors (cytologists and pathologists) will be blinded during the entire study. The primary outcome measure is the diagnosis yield. Secondary outcome measures are specimen quality. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT01774162 -
EUS-guided Fine Needle Biopsy With a New Core Histology Needle Versus Conventional Fine Needle Aspiration
|
N/A | |
Completed |
NCT00930410 -
Intra-ductal Confocal Endomicroscopy for Characterization of Pancreas and Bile Duct Tumor
|
N/A | |
Terminated |
NCT00198081 -
Use of Celecoxib in Patients With Intraductal Papillary Mucinous Neoplasms (IPMNs)
|
Phase 2 | |
Completed |
NCT00377936 -
EndoTAG-1 / Gemcitabine Combination Therapy to Treat Locally Advanced and/or Metastatic Adenocarcinoma of the Pancreas
|
Phase 2 | |
Active, not recruiting |
NCT02905578 -
A Phase 2 Trial of High-dose Ascorbate for Pancreatic Cancer (PACMAN 2.1)
|
Phase 2 | |
Completed |
NCT01446458 -
Phase I Study of Stereotactic Body Radiation Therapy and FOLFIRINOX in the Neoadjuvant Therapy of Pancreatic Cancer
|
Phase 1 | |
Recruiting |
NCT02789371 -
Comparing of Modified Wet Suction Technique and Dry Suction Technique for EUS-FNA of Solid Occupying Lesions
|
N/A | |
Unknown status |
NCT00683358 -
Human Leukocyte Antigen-A*2402-Restricted Tumor Vessel Specific Peptide Vaccination for Advanced Pancreatic Cancer
|
Phase 1/Phase 2 | |
Terminated |
NCT00683085 -
Human Leukocyte Antigen-A*02:01-restricted Tumor Vessel Specific Peptide Vaccination for Advanced Pancreatic Cancer
|
Phase 1/Phase 2 | |
Completed |
NCT02681796 -
Epidural Analgesia Use in Pancreatic Resections
|
Phase 1 | |
Recruiting |
NCT00690300 -
Docetaxel Plus Oxaliplatin as Therapy in Patients With Pancreatic Cancer
|
Phase 2 | |
Recruiting |
NCT02327065 -
Prospective Multi-center, Single Blinded, Randomized, Controlled Trial of EUS-FNB and EUS-FNA on Solid Occupying Lesion
|
N/A | |
Completed |
NCT01693419 -
S-1, Gemcitabine and Erlotinib for Advanced Pancreatic Cancer
|
Phase 2 |