Clinical Trials Logo
  1. Home
  2. Pancreas Neoplasms
  3. NCT03803930

Comparing of a 22G EUS Procore Fine Needle Biopsy Device and a 20G EUS Procore Fine Needle Biopsy Device

Pancreas Neoplasms Clinical Trial

Official title:
Comparing of a 22G EUS Procore Fine Needle Biopsy Device and a 20G EUS Procore Fine Needle Biopsy Device for Solid Pancreatic Lesions: a Prospective Multi-center, Randomized, and Controlled Trial

Clinical Trial Summary

The purpose of this study is to compare the diagnosis accuracy of 22G EUS Procore fine needle biopsy （FNB）device and 20G EUS Procore fine needle biopsy device for solid pancreatic lesions.

Clinical Trial Description

This is a single-blind, randomized, controlled trial. One thousand two hundred and twenty four patients with solid pancreatic lesions referred for EUS guided fine needle biopsy will be randomly assigned to 4 arms. For arm A1 which will be used with 22G EUS Procore fine needle biopsy device, the pass sequence is slow pull(SP)-modified wet suction technique(MWST)-slow pull(SP)-modified wet suction technique(MWST). For arm A2 with 22G EUS Procore fine needle biopsy device, the pass sequence is MWST-SP-MWST-SP. For arm B1 with 20G EUS Procore fine needle biopsy device, the pass sequence is SP-MWST-SP-MWST. For arm B2 with 20G EUS Procore fine needle biopsy device, the pass sequence is MWST-SP-MWST-SP. All procedures will be performed by experienced echoendoscopists, and the patients and assessors (cytologists and pathologists) will be blinded during the entire study. The primary outcome measure is the diagnosis yield. Secondary outcome measures are specimen quality. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03803930
Study type Interventional
Source Huazhong University of Science and Technology
Contact Bin Cheng
Phone +862783663333
Email b.cheng@tjh.tjmu.edu.cn
Status Not yet recruiting
Phase N/A
Start date March 1, 2019
Completion date August 1, 2020
View Details
See also
  Status Clinical Trial Phase
Completed NCT01774162 - EUS-guided Fine Needle Biopsy With a New Core Histology Needle Versus Conventional Fine Needle Aspiration N/A
Completed NCT00930410 - Intra-ductal Confocal Endomicroscopy for Characterization of Pancreas and Bile Duct Tumor N/A
Terminated NCT00198081 - Use of Celecoxib in Patients With Intraductal Papillary Mucinous Neoplasms (IPMNs) Phase 2
Completed NCT00377936 - EndoTAG-1 / Gemcitabine Combination Therapy to Treat Locally Advanced and/or Metastatic Adenocarcinoma of the Pancreas Phase 2
Active, not recruiting NCT02905578 - A Phase 2 Trial of High-dose Ascorbate for Pancreatic Cancer (PACMAN 2.1) Phase 2
Completed NCT01446458 - Phase I Study of Stereotactic Body Radiation Therapy and FOLFIRINOX in the Neoadjuvant Therapy of Pancreatic Cancer Phase 1
Recruiting NCT02789371 - Comparing of Modified Wet Suction Technique and Dry Suction Technique for EUS-FNA of Solid Occupying Lesions N/A
Terminated NCT00683085 - Human Leukocyte Antigen-A*02:01-restricted Tumor Vessel Specific Peptide Vaccination for Advanced Pancreatic Cancer Phase 1/Phase 2
Unknown status NCT00683358 - Human Leukocyte Antigen-A*2402-Restricted Tumor Vessel Specific Peptide Vaccination for Advanced Pancreatic Cancer Phase 1/Phase 2
Completed NCT02681796 - Epidural Analgesia Use in Pancreatic Resections Phase 1
Recruiting NCT00690300 - Docetaxel Plus Oxaliplatin as Therapy in Patients With Pancreatic Cancer Phase 2
Recruiting NCT02327065 - Prospective Multi-center, Single Blinded, Randomized, Controlled Trial of EUS-FNB and EUS-FNA on Solid Occupying Lesion N/A
Completed NCT01693419 - S-1, Gemcitabine and Erlotinib for Advanced Pancreatic Cancer Phase 2