Pain Clinical Trial
Official title:
The Feasibility of the PAINReportIt Guided Relaxation Intervention for Pain and Stress Symptoms in Adult Outpatients With Sickle Cell Disease
Our goal is to improve the self-management of pain and stress in adult outpatients with sickle cell disease (SCD) by determining the feasibility of a self-managed guided relaxation (GR) stress reduction intervention using a tablet-based mobile device. Currently, opioid analgesics are primarily used to treat SCD pain while self-managed behavioral modalities such as GR, are rarely used. Little is known about the effects or mechanisms of GR on pain and stress, in adults with SCD. Emerging evidence from the hypothalamic pituitary adrenal (HPA) axis theory offer insights for understanding the mechanisms. Adding GR as a supplement to analgesic therapies will address the paucity of self-management strategies for controlling pain in SCD. GR is a simple and cost-effective non-drug intervention that could reduce pain and stress in outpatients with SCD. GR is an intervention where outpatients with SCD are directed to listen to and view audio-visual recordings while they visualize themselves being immersed in that scene.
The investigator will recruit adult outpatients with sickle cell disease (SCD) from the
University of Florida Health Hematology Clinics and conduct study visits in a research room
located at the College of nursing.
The investigator will stratify participants on worst pain intensity (<=5 and >5) and randomly
assign 15 adults to attention control (stress/pain tracking; 12-min SCD experience
discussion) and 15 adults to experimental (stress/pain tracking; 12-min GR video clip)
groups.
The immediate intervention effects will be examined for pain (primary) and stress (secondary)
outcomes. Vital signs for determining relaxation responses (mediators) will be collected
immediately before and after the 12-min interventions.
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