Pectointercostal Fascial Plane Block Versus Transversus Thoracic Plane Block In Adult Cardiac Surgery Patients

Pain, Post Operative Clinical Trial

Official title:

Ultrasound Guided Pectointercostal Fascial Plane Block Versus Transversus Thoracic Plane Block In Adult Cardiac Surgery Patients: A Comparative Study

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05323305
• Other study ID #: 0305468
• Status: Recruiting
• Phase: N/A
• Start date: March 30, 2022
• Est. completion date: December 2022

Study information

• Verified date: March 2022
• Source: Alexandria University
• Contact: Islam Omar, MD
• Phone: +201227851759
• Email: i_omar12[@]alexmed.edu.eg
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The study will be designed to compare the analgesic effect of ultrasound-guided pectointercostal fascial plane block versus tansversus thoracic plane block in adult cardiac surgery.

Description:

A prospective study will be carried out in Alexandria Main University Hospitals on 60 adult patients planned for elective cardiac surgery, after approval of the Ethical Committee of Faculty of Medicine, Alexandria, and having an informed written consent taken from patients included in the study. Patients will be categorized into two equal groups; group P (n=30)) will receive ultrasound-guided pectointercostal fascial plane block and group T (n=30) will receive ultrasound-guided transversus thoracic plane block. All patients will receive the ultrasound-guided block after induction of anesthesia and an equal booster dose of the same block before extubation in the ICU. Patients in both groups will also receive an ultrasound-guided bilateral serratus anterior plane block before extubation.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: December 2022
• Est. primary completion date: October 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

1. Adult patient.

2. Elective cardiac surgery.

Exclusion Criteria:

1. Refusal to participate.

2. Redo or urgent cardiac surgery.

3. Local infection of the skin at the site of needle puncture.

4. Allergy to bupivacaine.

5. Coagulation disorders.

6. Clinically significant liver or kidney disease, heart failure, moderate to severe pulmonary hypertension.

7. when extubation is intentionally planned to be delayed

Related Conditions & MeSH terms

• Pain, Post Operative
• Pain, Postoperative

Intervention

Procedure:
• ultrasound guided regional block
Bupivacaine injection by the use of ultrasound in the pectointercostal fascial plane in one group and in the trasversus thoracic plane in the other group.

Locations

Country	Name	City	State
Egypt	Alexandria University Hospitals	Alexandria

Sponsors (1)

Lead Sponsor	Collaborator
Alexandria University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	the analgesic effectiveness of the two blocks on midline sternotomy pain,	Postoperative pain evaluation after extubation will be done using the Visual Analogue Scale (VAS). a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between 0 "no pain" and 10 "worst pain."	from end of surgery till discharge from ICU (96 hours)
Secondary	pulmonary complications	atelectasis and pneumonia	from end of surgery till discharge from ICU (96 hours)
Secondary	length of stay in ICU	days from admission till discharge from ICU	average 4 days