Mepivacaine vs. Bupivacaine Spinal Anesthetic in Total Knee Arthroplasty

Pain Management Clinical Trial

Official title: Mepivacaine vs. Bupivacaine Spinal Anesthetic in Total Knee Arthroplasty, a Randomized Controlled Clinical Trial

Status Completed

Clinical Trial Summary

The purpose of this study is to determine if a shorter-acting spinal anesthetic called mepivacaine has advantages over a longer-acting medication called bupivacaine.

Clinical Trial Description

Different medications last for different amounts of time and can be changed depending on the length of the procedure. A short acting spinal is generally used for procedures lasting less than 90 minutes. A longer acting medication would be any that lasts longer than 90 minutes. These medications not only block the signals that travel along the pain nerves, they also prevent the signals that tell the patients muscles to move. This means that after a total knee replacement a patient may delayed in their ability to get up and start walking early after surgery. Walking early in the recovery has been shown to decrease the rate of pulmonary embolism and death. Ambulating early is also important to prevent loss of strength, constipation, pneumonia and urinary retention. ;

Related Conditions & MeSH terms

• Ambulatory Surgical Procedures
• Anesthesia, Spinal
• Arthroplasty, Replacement, Knee
• Early Ambulation
• Pain Management

• NCT number: NCT02980926
• Study type: Interventional
• Source: Henry Ford Health System
• Status: Completed
• Phase: Phase 4
• Start date: December 2016
• Completion date: March 2017