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Ketone Supplementation, Glucose Control, and Cardiovascular Function

Overweight and Obesity Clinical Trial

Official title:
The Effects of Exogenous Ketone Supplementation on Cardiovascular Function and Glucose Control

Clinical Trial Summary

Post-prandial hyperglycemic excursions induce a cascade of deleterious effects on the body, including increased inflammation, production of reactive oxygen species, and impaired cardiovascular function. Ingestion of an exogenous oral ketone supplement blunts hyperglycemia in response to an oral glucose tolerance test. Accordingly, it is hypothesized that exogenous ketone supplement ingestion prior to a meal could be an effective strategy for blunting postprandial hyperglycemia. Therefore, the purpose of this study is to investigate the effect of short-term (14-days) pre-meal exogenous ketone supplementation on glucose control, cardiovascular function, inflammation, and oxidative stress in individuals at an elevated risk of type 2 diabetes.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03817749
Study type Interventional
Source University of British Columbia
Contact
Status Completed
Phase N/A
Start date February 6, 2019
Completion date December 31, 2020
View Details
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