Acute Myocardial Infarction (AMI) Clinical Trial
Official title:
Angiography Derived Index of Microcirculatory Resistance in Patients With Acute Myocardial Infarction
| NCT number | NCT05696379 |
| Other study ID # | 2022-0878 |
| Secondary ID | |
| Status | Completed |
| Phase | |
| First received | |
| Last updated | |
| Start date | June 1, 2017 |
| Est. completion date | May 31, 2022 |
| Verified date | December 2022 |
| Source | Second Affiliated Hospital, School of Medicine, Zhejiang University |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Observational |
Coronary microcirculatory dysfunction has been known to be prevalent even after successful revascularization of acute myocardial infarction (AMI) patients, and has been shown to be associated with poor prognosis. Angiography derived index of micro-circulatory resistance (Angio-IMR) is a novel pressure-wire free approach to assess coronary microvascular disease with great diagnostic performance. The current study will further investigate the prognostic value of Angio-IMR in patients with AMI in multicenter retrospective cohort.
| Status | Completed |
| Enrollment | 5000 |
| Est. completion date | May 31, 2022 |
| Est. primary completion date | May 31, 2022 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years and older |
| Eligibility | Inclusion Criteria: - Acute myocardial infarction patients who underwent successful percutaneous coronary intervention Exclusion Criteria: - No appropriate coronary angiography images (inferior image quality, image loss, severe arteries overlap, or significant artifact) - Previous coronary artery bypass graft |
| Country | Name | City | State |
|---|---|---|---|
| China | Second Affiliated Hospital, School of Medicine, Zhejiang University | Hangzhou | Zhejiang |
| Lead Sponsor | Collaborator |
|---|---|
| Second Affiliated Hospital, School of Medicine, Zhejiang University | RenJi Hospital, Shengjing Hospital |
China,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Cardiac death or readmission for heart failure in 1 month | Incidence of cardiac death or readmission for heart failure during first 1 month follow-up. | 1 month | |
| Primary | Cardiac death or readmission for heart failure in 6 months | Incidence of cardiac death or readmission for heart failure during first 6 months follow-up. | 6 month | |
| Primary | Cardiac death or readmission for heart failure in 1 year | Incidence of cardiac death or readmission for heart failure during first 1 year follow-up. | 1 year | |
| Primary | Cardiac death or readmission for heart failure in 2 years | Incidence of cardiac death or readmission for heart failure during first 2 years follow-up. | 2 year |
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