Clinical Trials Logo

Clinical Trial Summary

- 2D Echocardiography with color Doppler assessment: It will be done within 24 h after PPCI - Peripheral blood samples were obtained within 48 hours after acute MI, and the serum will be frozen at -70°C until tested for Galactin-3 level. - Follow up 2D Doppler echocardiography: will be repeated at 40 days of the event.


Clinical Trial Description

2D Echocardiography with color Doppler assessment: It will be done within 24 h after PPCI. Measurements will be as following: 1. Pulsed wave (PW) Doppler will be performed in the apical 4chamber view within a 3 mm sample volume at the tip of the mitral leaflets to obtain mitral inflow velocities to assess LV filling. 2. E (early diastolic)/A (late diastolic) - Using PW Doppler, the peak E and A velocities were recorded, then the ratio of E/A will be calculated. 3. IVRT (isovolumic relaxation time) - derived by placing the cursor of Continuous wave (CW) Doppler in the LV outflow tract to simultaneously display the end of aortic ejection and the onset of mitral inflow. 4. Deceleration time (DT) - from the peak of E wave to baseline. 5. E/e'- PW tissue Doppler imaging (TDI) was performed in the apical views to acquire mitral annular velocities. The sample volume will be positioned at or 1 cm within the mitral leaflet's septal and lateral insertion sites. 6. Left atrial volume and left atrial volume index (LAVI) - The maximal left atrial (LA) volume measured from the apical four-chamber view using the modified Simpson method in end-systole before mitral valve opening. The LAVI obtained for all patients by dividing the LA volume by the body surface area. Biochemical measurements: Peripheral blood samples were obtained within 48 hours after acute MI, and the serum will be frozen at -70°C until tested for Galactin-3 level. Follow up 2D Doppler echocardiography: All previous echocardiographic measurements will be repeated at 40 days of the event. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05107076
Study type Observational
Source Assiut University
Contact Mariam Hanna, Resident
Phone +201069862210
Email mariam.abdelmalak@yahoo.com
Status Recruiting
Phase
Start date November 2021
Completion date May 2023

See also
  Status Clinical Trial Phase
Recruiting NCT06013813 - Conventional vs. Distal Radial Access Outcomes in STEMI Patients Treated by PCI N/A
Terminated NCT04542889 - Coronary Microcirculation Assessment After Primary Angioplasty in Myocardial Infarction N/A
Recruiting NCT04951856 - Evolocumab or Normal Strategies to Reach LDL Objectives in Acute Myocardial Infarction Upbound to PCI Phase 4
Terminated NCT04459299 - CorPath GRX STEMI Study
Recruiting NCT05557019 - Semi Occlusion of the Coronary Sinus as an Adjunct to PCI in STEMI Patients, FIH Clinical Study N/A
Completed NCT03527940 - Prognostic Markers of Patients With STEMI
Not yet recruiting NCT03264859 - NGAL and Its Association With the No-reflow Phenomenon in ST-elevation Myocardial Infarction N/A
Not yet recruiting NCT03182855 - Cangrelor vs. Ticagrelor for Early Platelet Inhibition in STEMI Phase 4
Not yet recruiting NCT03266289 - Evaluation of Short Term Outcome of Different Bifurcation Stenting Techniques at Assuit University Cath. Lab N/A
Withdrawn NCT04566289 - Observational Registry to Evaluate Real World Usage of PiCSO Impulse System in STEMI Patients as Part of Post-marketing Surveillance
Completed NCT04289012 - HELicobacter Pylori Screening in Patients With Acute Myocardial Infarction Pilot Study N/A
Not yet recruiting NCT04185077 - Bivalirudin in Late PCI for Oatients With STEMI Phase 4
Completed NCT03609346 - Asian Registry of the BioFreedom Stent for STEMI Patients
Recruiting NCT02998853 - Non Culprit Functional Evaluation With 3D Angio QFR in STEMI PCI Procedure N/A
Completed NCT03677180 - National Cardiogenic Shock Initiative
Completed NCT03507777 - ILUMIEN IV: OPTIMAL PCI N/A
Recruiting NCT03863327 - EKG Criteria and Identification of Acute Coronary Occlusion
Completed NCT03070496 - Multicenter Cohort of STEMI Patients N/A
Active, not recruiting NCT03874338 - CLEAR SYNERGY Neutrophil Substudy
Withdrawn NCT05497011 - A Study to Evaluate the Safety and Efficacy of PiCSO in Anterior STEMI Patients N/A