Respiratory Syncytial Virus Infections Clinical Trial
Official title:
Epidemiology and Transmission of Streptococcus Pneumoniae and Respiratory Syncytial Virus in Children and Elderly: a Household-based Prospective Cohort Study
This household-based prospective cohort study aims to stablish the household transmission of Respiratory syncytial virus and S. pneumoniae especially in the elderly and infants/children as well as inter-relationship between S. pneumoniae and Respiratory syncytial virus.
Status | Not yet recruiting |
Enrollment | 240 |
Est. completion date | July 31, 2026 |
Est. primary completion date | July 31, 2026 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | N/A and older |
Eligibility | Inclusion Criteria: - Indicator case: Babies under 5 months of age were born in Mackay Children's Hospital and had no acute respiratory infection-like symptoms that required medical intervention when they agreed to participate in the trial. - Family members: family members living with the Indicator case, including 2-5 years old siblings, parents and grandparents over 65 years old. - Willing to sign the informed consent form and agree to join the official LINE account to receive research tracking. Exclusion Criteria: - Babies older than 5 months - Co-morbid medical conditions of the baby such as chronic lung disease, cyanotic congenital heart disease, neuromuscular disease and a primary immunodeficiency. - Family members who do not live with the Indicator case - Family with grandparents younger than 65 years old - Someone living with family members refuses to participate in the research. - Unwilling to sign informed consent form or refuse to join the official LINE account to receive tracking. |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
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Mackay Memorial Hospital | Merck Sharp & Dohme Corp. |
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* Note: There are 40 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Household transmission of Streptococcus pneumoniae and Respiratory syncytial virus | The primary endpoint is the Streptococcus pneumoniae and Respiratory syncytial virus isolation rates in children and their household contacts of different family type. | 2 years | |
Primary | The serotype of Streptococcus pneumoniae and Respiratory syncytial virus in post-Prevenar 13 era | The secondary endpoint is the serotype of Streptococcus pneumoniae and Respiratory syncytial virus in post-Prevenar 13 era. | 2 years |
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