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Early Prediction of QFR in STEMI-I — EARLYmyo-QFR-I  

ST Segment Elevation Myocardial Infarction Clinical Trial

Official title:
EARLY Microvascular Dysfunction Prediction Using Quantitative Flow Ratio After ST-segment Elevation MYOcardial Infarction (EARLY-MYO-QFR I)

Clinical Trial Summary

The study intends to provide important data on whether the noval method using quantitative flow ratio could predict microvascular dysfunction.

Clinical Trial Description

Microvascular dysfunction (MVD) is a serious complication of PCI, which happens frequently after STEMI and always correlates with a poor prognosis. However, precise and simplified assessment of MVD is difficult, especially in the acute phase of STEMI patients. Resent studies suggested that FFR could be overestimated when MVD exists. But whether the overestimated value of FFR caused by CMR defined MVO could reflect microcirculation function is still unclear.

This study is a retrospective study using STEMI patients with TFG 2/3 of the infarct vessel on initial angiography and presumed culprit lesion ≥50% as the population. Contrast-enhanced CMR was performed 5 days after PCI as the reference standard. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03780335
Study type Observational
Source RenJi Hospital
Contact
Status Completed
Phase
Start date January 1, 2015
Completion date September 30, 2018
View Details
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