Acute ST Segment Elevation Myocardial Infarction Clinical Trial
Official title:
Performance of Bioresorbable Scaffold in Primary Percutaneous Intervention of ST Elevation Myocardial Infarct (BVS in STEMI)
Patients presenting with acute ST elevation myocardial infarct urgently need
revascularization. Standard of care is establishing bloodflow through the coronary vessels
using thrombus aspiration catheter, and securing the result by using a metallic drug eluting
stent. New kinds of non-metallic bioresorbable stents are now available. They have however
challenges in structural strength.
The investigators want to compare the new bioresorbable scaffold with traditional metallic
stents in this setting in a prospective, randomized, non-blinded, multicenter study in 120
patients. The investigators will use an imaging technique, optical coherence tomography, to
evaluate the results after 12 months.
The investigators also want to see if modern multislice computed tomography can give useful
information in the follow-up of stented coronary arteries after 12 and 24 months.
Patients presenting with ST elevation myocardial infarction for primary PCI (percutaneous coronary intervention) will be screened. After thrombus aspiration, patient will be asked for oral consent if TIMI flow 2-3. Patient will then be randomized between drug eluting stent (Xience pro, Abbott Vascular Solutions) and bioresorbable scaffold (Absorb, Abbott Vascular Solutions). Optical coherence tomography (OCT) will be performed before stenting and after final result. Stent will be deployed without further predilatation if possible. Follow up at 12 months (clinical, angio with OCT and multislice CT coronary angiogram (MSCT-CA)) and 24 months (MSCT-CA). ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT06435728 -
Predictive Value of Combining AccuIMR and AccuFFR in Patients With STEMI
|
||
| Completed |
NCT02914795 -
Platelet Function in Resuscitated Patients
|
||
| Recruiting |
NCT00697021 -
Thromboelastography As An Assessment Tool for Possible Clopidogrel and Aspirin Resistance
|
Phase 3 | |
| Completed |
NCT05949515 -
Retrospective Evaluation of SuperSaturated Oxygen (SSO2) Therapy Clinical Utility
|
||
| Completed |
NCT02828683 -
Safety and Efficacy of TCD-10023 (Ultimaster) Drug-eluting Stent in STEMI Patients - MASTER Study
|
N/A | |
| Completed |
NCT01986803 -
ABSORB STEMI: the TROFI II Study
|
N/A | |
| Active, not recruiting |
NCT01878344 -
Effects of N-acetyl Cysteine During Primary Percutaneous Coronary Intervention
|
Phase 3 | |
| Withdrawn |
NCT02048085 -
Comparing Ticagrelor and Clopidogrel Pharmacodynamics After Thrombolysis
|
Phase 4 | |
| Completed |
NCT04463251 -
Study to Evaluate the Effect on Parameters of Systemic Inflammation and Disease Outcomes and Safety of RPH-104 in Subjects With Acute ST-elevation Myocardial Infarction
|
Phase 2 | |
| Active, not recruiting |
NCT02943954 -
FLOW Evaluation to Guide Revascularization in Multi-vessel ST-elevation Myocardial Infarction
|
N/A | |
| Completed |
NCT02298088 -
Ticagrelor in Patients With ST Elevation Myocardial Infarction Treated With Pharmacological Thrombolysis
|
Phase 3 | |
| Completed |
NCT01787110 -
An Efficacy and Outcome Study of Supplemental Oxygen Treatment in Patients With Suspected Myocardial Infarction
|
Phase 3 | |
| Recruiting |
NCT03137212 -
Safety and Efficacy of Percutaneous Coronary Intervention Combined With Thrombolysis at Different Time
|
N/A | |
| Not yet recruiting |
NCT05802667 -
A Cohort Study of Correlation Between Mast Cells and Prognosis in Patients With Acute Myocardial Infarction
|
||
| Completed |
NCT04730778 -
Predictive Value of CHA2DS2VASC Score for Contrast-induced Nephropathy After Primary Percutaneous Coronary Intervention in ST-segment Elevation Myocardial Infarction Patients
|