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NCT00952224 Clinical Trial

Myocardial Salvage Assessed by Cardiovascular Magnetic Resonance - Impact on Outcome

ST-Elevation Myocardial Infarction Clinical Trial

Official title:
Prognostic Significance and Determinants of Myocardial Salvage Assessed by Cardiovascular Magnetic Resonance in Acute Reperfused Myocardial Infarction

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00952224
Other study ID # Leipzig MR 1
Secondary ID
Status Completed
Phase N/A
First received August 3, 2009
Last updated August 4, 2009
Start date November 2006
Est. completion date March 2009

Study information
Verified date August 2009
Source University of Leipzig
Contact n/a
Is FDA regulated No
Health authority Germany: Ethics Commission
Study type Observational

Clinical Trial Summary

In acute myocardial infarction cardiovascular magnetic resonance imaging can retrospectively detect the myocardium at risk and the irreversible injury. This allows for quantifying the extent of salvaged myocardium after reperfusion as a potential strong end point for clinical trials and outcome. The aim of the present study is to determine the prognostic significance and determinants of myocardial salvage assessed by CMR in reperfused ST-elevation myocardial infarction (STEMI).

Recruitment information / eligibility
Status Completed
Enrollment 267
Est. completion date March 2009
Est. primary completion date May 2008
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- ST-elevation myocardial infarction < 12 hours

- primary percutaneous coronary intervention

Exclusion Criteria:

- previous myocardial infarction

- prior fibrinolysis

- contraindications to CMR at study entry (such as implanted pacemakers, defibrillators, claustrophobia or metallic intracranial implants)

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Intervention

Other:
• magnetic resonance imaging
magnetic resonance imaging is used for prognosis assessment

Locations
Country Name City State
Germany University of Leipzig - Heart Center Leipzig

Sponsors (1)
Lead Sponsor Collaborator
University of Leipzig

Country where clinical trial is conducted

Germany, 

Outcome
Type Measure Description Time frame Safety issue
Primary Major adverse cardiac events 6 months No
Secondary Mortality 6 months No
See also
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