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Clinical Trial Details — Status: Active, not recruiting

Administrative data

NCT number NCT05481242
Other study ID # AOAPE
Secondary ID
Status Active, not recruiting
Phase
First received
Last updated
Start date January 1, 2011
Est. completion date December 31, 2025

Study information

Verified date November 2023
Source Shengjing Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This multi-center retrospective study collected clinical, laboratory, and CT pulmonary angiography parameters with acute pulmonary embolism patients from admission to predict adverse outcomes within 30 days after admission into hospital.


Description:

This multi-center retrospective study collected clinical, laboratory, and CT pulmonary angiography parameters with acute pulmonary embolism patients from admission to predict adverse outcomes within 30 days after admission into hospital. Eligible patients were collected to develop and evaluate a simple predictive model for predicting the adverse outcomes. The discriminatory power was evaluated by comparing the nomogram to the established risk stratification systems. The consistency of the nomogram was evaluated using the validation cohort.


Recruitment information / eligibility

Status Active, not recruiting
Enrollment 2000
Est. completion date December 31, 2025
Est. primary completion date January 31, 2021
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - age of = 18 years and a pulmonary embolism diagnosis based on CT pulmonary angiography Exclusion Criteria: - pregnancy - reception of reperfusion treatment before admission - missing data regarding CT parameters, echocardiography, cardiac troponin I (c-Tn I), and N-terminal-pro brain natriuretic peptide (NT-pro BNP) levels.

Study Design


Related Conditions & MeSH terms


Intervention

Other:
retrospective observational study
retrospective observational study

Locations

Country Name City State
China Shenjing Hospital of CHINA MEDICAL UNIVERSITY Shenyang Liaoning

Sponsors (1)

Lead Sponsor Collaborator
Shengjing Hospital

Country where clinical trial is conducted

China, 

Outcome

Type Measure Description Time frame Safety issue
Primary Adverse outcomes The endpoints of deterioration in this study were defined as the occurrence of any adverse clinical outcomes from medical records and follow-up within 30 days of admission such as death, mechanical ventilation, cardiopulmonary resuscitation, and the need for life-saving vasopressor or reperfusion treatment .In each centre, the researchers for evaluating endpoints were blind to collect and to measure study parameters. 30 days
Secondary Adverse outcomes The endpoints of deterioration in this study were defined as the occurrence of any adverse clinical outcomes from medical records and follow-up within 2 years of admission such as death, mechanical ventilation, cardiopulmonary resuscitation, and the need for life-saving vasopressor or reperfusion treatment .In each centre, the researchers for evaluating endpoints were blind to collect and to measure study parameters. 2 years
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