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Clinical Trial Summary

This study is a single-arm,exploratory clinical study, to evaluate the effectiveness and safety of apatinib mesylate combined with albumin-bound paclitaxel for second-line treatment of advanced triple negative breast cancer.


Clinical Trial Description

This is a exploratory, single-arm, open-label trial. The investigator's primary purpose is to explore that PFS and safety of apatinib combined with albumin-bound paclitaxel for treatment of advanced triple negative breast cancer. In treatment period, patients will be administrated apatinib plus albumin-bound paclitaxel, every 21 days for 1 cycle, until disease progression, toxicity intolerance, withdrawal of informed consent, patients judged must be terminated study termination. The imaging evaluation was performed according to the RECIST 1.1 criteria every 6 weeks. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05019690
Study type Interventional
Source Fujian Cancer Hospital
Contact weiwei Huang
Phone 13763893896
Email huangstudenth@163.com
Status Not yet recruiting
Phase Phase 1/Phase 2
Start date October 1, 2021
Completion date December 31, 2023

See also
  Status Clinical Trial Phase
Terminated NCT04927884 - A Study of Sacituzumab With Chemoimmunotherapy to Treat Advanced Triple-Negative Breast Cancer After Prior Therapies Phase 1/Phase 2
Terminated NCT03861403 - A Dose Escalation and Expansion Study of TRX518 in Combination With Cyclophosphamide Plus Avelumab in Advanced Solid Tumors Phase 1
Withdrawn NCT02661100 - A Trial of CDX-1401 in Combination With Poly-ICLC and Pembrolizumab, in Previously Treated Advanced Solid Tumor Patients Phase 1/Phase 2
Not yet recruiting NCT05686720 - Single-arm, Open-label Clinical Study of SZ011 in the Treatment of Advanced Triple Negative Breast Cancer Early Phase 1