Other Clinical Trial - Injections of Glutamic Acid Decarboxylase (GAD) for

Clinical Trial Summary

This study will evaluate the effects of 3 intra-nodal injections of GAD-alum (Diamyd), together with oral vitamin D supplementation. Safety and feasibility of the treatment will be evaluated and also effects on the immune system and on the preservation of endogenous insulin production.

See also
	Status	Clinical Trial	Phase
	Completed	`NCT06167616` - Infections and Latent Autoimmune Diabetes in Adults
	Recruiting	`NCT06098729` - Digital Exercise for Middle-Aged Adults With Type 1 Diabetes and Other Absolute Insulin Deficiency Diabetes	N/A

See also

Status

Clinical Trial

Phase

Completed

NCT06167616 - Infections and Latent Autoimmune Diabetes in Adults

Recruiting

NCT06098729 - Digital Exercise for Middle-Aged Adults With Type 1 Diabetes and Other Absolute Insulin Deficiency Diabetes

N/A

Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.

Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.

Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

NCT number	NCT04262479
Study type	Interventional
Source	Norwegian University of Science and Technology
Contact
Status	Completed
Phase	Phase 2
Start date	March 2, 2020
Completion date	May 5, 2022

Injections of Glutamic Acid Decarboxylase (GAD) for LADA Type of Diabetes — GADinLADA

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms